Maternal Heart Health Predicts CVD Onset in Offspring
Offspring of mothers with ideal CV health live nine more years free from CVD than offspring of mothers with poor CV health
FRIDAY, Nov. 6, 2020 (HealthDay News) -- Offspring of parents with ideal cardiovascular health (CVH) have increased cardiovascular disease (CVD)-free survival, with maternal CVH a more robust predictor of offspring's CVD-free survival than paternal CVH, according to a study published online Nov. 5 in the European Journal of Preventive Cardiology.
James M. Muchira, R.N., Ph.D., from the Vanderbilt University School of Nursing in Nashville, Tennessee, and colleagues examined the association between parental CVH and time to CVD onset in offspring in a study comprising 5,967 offspring-mother-father trios derived from the Framingham Heart Study. The seven American Heart Association CVH metrics attained at ideal levels were used to define CVH score.
The researchers identified 718 incident CVD events during 71,974 person-years of follow-up among the offspring. The overall incidence rate was 10 per 1,000 person-years for CVD. Compared with offspring of mothers with poor CVH, offspring of mothers with ideal CVH lived nine more years free from CVD. Compared with maternal ideal CVH, maternal poor CVH was associated with an increased risk for early onset of CVD (adjusted hazard ratio, 2.09). There was no significant association in the risk for CVD-free survival by paternal CVH categories.
"Family-based interventions should occur during pregnancy and very early in the child's life, so that the real impact of protective cardiovascular health tracks into adulthood," Muchira said in a statement.