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Middle-Ear Steroid Effective in Eosinophilic Otitis Media

Triamcinolone treatment of the middle ear is better than topical betamethasone

THURSDAY, Dec. 21 (HealthDay News) -- Treatment of the middle ear with triamcinolone acetonide is more effective than topical betamethasone drops at controlling otorrhea in patients with bronchial asthma-associated eosinophilic otitis media, according to a report published in the December issue of the Annals of Allergy, Asthma and Immunology.

Yukiko Iino, M.D., of Teikyo University School of Medicine in Tokyo, and colleagues evaluated the effectiveness of triamcinolone, which was introduced into the mesotympanum and eustachian tube, in 43 ears of 24 patients with eosinophilic otitis media. The results were compared with 27 ears of 14 patients who received topical betamethasone.

Otorrhea was controlled for more than three weeks in 35 ears of the triamcinolone-treated group after one treatment, for an efficacy rate of 81 percent. The efficacy rate was 26 percent (seven ears) in controls. The triamcinolone group also had improved mean air conduction hearing in the speech frequency range. Bone conduction hearing deterioration was rarely seen, the report indicates.

"The instillation of triamcinolone acetonide into the mesotympanum and eustachian tube is an effective treatment for patients with eosinophilic otitis media," the authors conclude.

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