August 2007 Briefing - Allergy

Here are what the editors at HealthDay consider to be the most important developments in Allergy for August 2007. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

High Indoor Particulate Matter Linked to Worse Lung Disease

FRIDAY, Aug. 31 (HealthDay News) -- People with chronic obstructive pulmonary disease, or COPD, who live in homes with high levels of particulate matter that is 2.5 micrometers or less in diameter (PM2.5) tend to have poorer health, according to study findings published in the Sept. 1 issue of the American Journal of Respiratory and Critical Care Medicine.

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Flavoring Ingredient Linked to Workers' Lung Disease

FRIDAY, Aug. 31 (HealthDay News) -- Following recent studies linking lung disease to exposure to food-processing flavorings, researchers in the Netherlands have found an association between an agent used in the production of diacetyl -- used for butter flavoring -- and bronchiolitis obliterans syndrome. The research is published in the Sept. 1 issue of the American Journal of Respiratory and Critical Care Medicine.

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Hand Eczema Extent is a Long-Term Prognostic Factor

FRIDAY, Aug. 31 (HealthDay News) -- The extent of hand eczema is a strong negative long-term prognostic factor, confirming a previous study, while morphology does not add any significant prognostic information, according to study findings published in the September issue of the Journal of Investigative Dermatology.

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Pollen, House Mites Have Different Effects on Asthma

WEDNESDAY, Aug. 29 (HealthDay News) -- House dust mites and pollens are associated with different effects on disease of the airways, according to a report published in the August issue of the Annals of Allergy, Asthma & Immunology.

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Effects of Aeroallergens on Children Increase with Age

TUESDAY, Aug. 28 (HealthDay News) -- Rates of aeroallergen sensitivity in children are high and increase as children get older, whereas perennial allergens predominate in children under the age of 3 years, according to a study published in the August issue of the Annals of Allergy, Asthma & Immunology.

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Immunodeficiency Often Goes Undiagnosed

MONDAY, Aug. 27 (HealthDay News) -- Patients with symptoms of primary immunodeficiency often go undiagnosed, which denies them the opportunity to receive appropriate specialist care, researchers report in the August issue of the Annals of Allergy, Asthma & Immunology.

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Asthma Risk Linked to Gene Variants and Auto Pollution

WEDNESDAY, Aug. 22 (HealthDay News) -- Proximity to major roads is associated with substantially greater risk of asthma in children who are genetically susceptible to the disease, according to a report published online Aug. 21 in the journal Thorax.

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Air Pollution Affects Young Adults' Cardiovascular Health

TUESDAY, Aug. 21 (HealthDay News) -- Exposure to air pollution is associated with a variety of simultaneous cardiovascular effects in healthy adults, including systemic inflammation, oxidative stress, blood coagulation and autonomic dysfunction, according to the results of a study published in the Aug. 15 issue of the American Journal of Respiratory and Critical Care Medicine.

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Chronic Sinusitis Linked to Smell Impairment

TUESDAY, Aug. 21 (HealthDay News) -- Several illnesses, including chronic sinusitis, are significantly associated with smell disturbance in managed care patients, researchers report in the August issue of the Archives of Otolaryngology - Head & Neck Surgery.

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Second-Line Antibiotics More Effective in Acute Bronchitis

THURSDAY, Aug. 16 (HealthDay News) -- In patients with acute exacerbations of chronic bronchitis, second-line antibiotics may be more effective than first-line antibiotics, according to study findings published in the August issue of Chest.

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Childhood Asthma Associated with Cytokine Response

WEDNESDAY, Aug. 15 (HealthDay News) -- Production of interleukin-5 (IL-5) T-cell cytokines in response to the house dust mite, the most common local inhalant allergen, is associated with the development of asthma in 5-year-old children, according to study findings published in the August issue of the Journal of Allergy and Clinical Immunology.

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Family History, Home Factors Boost Child's Risk of Wheezing

TUESDAY, Aug. 14 (HealthDay News) -- Children from families with a history of asthma have a higher risk of developing respiratory symptoms if they are also exposed to parental smoking or dust mite antigen, according to study findings published in the August issue of the Journal of Allergy and Clinical Immunology.

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Allergic Rhinitis Puts Students at Disadvantage on Tests

MONDAY, Aug. 13 (HealthDay News) -- Teenagers with allergic rhinitis symptoms are more likely to drop a grade on their exams during peak allergy season compared to winter exams, and more likely to score worse if they are taking sedating antihistamines, according to a report in the August issue of the Journal of Allergy and Clinical Immunology.

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Crohn's Risk Lower in Children Exposed to Farm Animals

MONDAY, Aug. 6 (HealthDay News) -- Contact with farm animals during infancy, which is thought to protect against childhood allergies, may have a similar effect on juvenile Crohn disease and ulcerative colitis, researchers report in the August issue of Pediatrics.

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Many Workers Suffer from Hand Contact Dermatitis

FRIDAY, Aug. 3 (HealthDay News) -- Health care workers and machine operators are among the most likely to be exposed to allergens that cause hand contact dermatitis, largely due to their use of rubber gloves, researchers report in the August issue of the Journal of the American Academy of Dermatology.

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Tobacco Additives May Be Harmful to Public Health

THURSDAY, Aug. 2 (HealthDay News) -- The tobacco industry has experimented with hundreds of additives in cigarettes that should require regulatory oversight, including 100 that may enhance the addictive effects of nicotine, sweeten the taste of tobacco, and mask the odor of secondhand smoke, according to a study published in the August issue of American Journal of Public Health.

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Patients With Oral Diseases May Have Contact Allergies

WEDNESDAY, Aug. 1 (HealthDay News) -- Contact allergies, particularly to potassium dicyanoaurate, nickel sulfate and gold sodium thiosulfate, are common in patients with oral diseases, such as stomatitis and gingivitis, according to a study in the August issue of the Journal of the American Academy of Dermatology.

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