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Patients With Oral Diseases May Have Contact Allergies

Allergy to certain compounds more common in those with a range of diseases

WEDNESDAY, Aug. 1 (HealthDay News) -- Contact allergies, particularly to potassium dicyanoaurate, nickel sulfate and gold sodium thiosulfate, are common in patients with oral diseases, such as stomatitis and gingivitis, according to a study in the August issue of the Journal of the American Academy of Dermatology.

Mark D. P. Davis, M.D., of the Mayo Clinic, Rochester, Minn., and colleagues conducted a study of 331 patients with a range of oral diseases such as burning mouth syndrome, lichenoid tissue reaction, cheilitis, stomatitis and gingivitis who were tested for 85 oral antigens including flavorings, preservatives, dental acrylates, medications and metals.

Patch tests yielded 341 positive results in 148 patients, of whom 90 tested positive for two or more allergens. There were 221 clinically relevant results.

"Although allergic contact dermatitis to metals is common in patients with oral lichenoid lesions, our results indicate that metal allergies are seen in patients with other oral diseases," the authors wrote. "In addition, the high frequency of positive reactions to flavorings and preservatives emphasizes the need to use a comprehensive allergen series when evaluating patients with oral disease."

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