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Green Tea Seems to Stem Spread of Prostate Cancer

Polyphenols control proliferation of malignant cells

WEDNESDAY, Dec. 1, 2004 (HealthDayNews) -- Green tea appears to inhibit the spread of prostate cancer in a number of ways, says a study in the Dec. 1 issue of Cancer Research.

In research with mice, scientists from the University of Wisconsin and Case Western Reserve University in Cleveland found green tea polyphenols (GTP) target molecular pathways that control the proliferation and spread of prostate tumor cells. The polyphenols also inhibit the growth of blood vessels that feed prostate tumors.

"Consumption of GTP led to reduced levels of IGF-1 (insulin-like growth factor-1)," study senior author Hasan Mukhtar, of the department of dermatology at the University of Wisconsin, said in a prepared statement.

"GTP also led to increased levels of one of the binding proteins for IGF-1, the insulin growth factor binding protein-3. These observations bear significance in light of studies that indicate increased levels of IGF-1 are associated with increased risk of several cancers, such as prostate, breast, lung and colon," Mukhtar said.

More information

The American Cancer Society has more about prostate cancer.

SOURCE: American Association for Cancer Research, news release, Dec. 1, 2004
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