TUESDAY, June 4, 2002 (HealthDayNews) -- New studies challenge the cost-effectiveness of COX-2 drugs compared to traditional non-steroidal anti-inflammatory (NSAIDs), such as ibuprofen and naproxen, in treating arthritis, acute pain and other disorders.
The studies were done by Express Scripts Inc., one of the nation's largest pharmacy benefit management firms, and presented today at its annual Outcomes Conference.
The studies found that prescription COX-2 drugs such as Celebrex, Vioxx and Bextra were as effective as NSAIDS but much more expensive. Some studies say the extra cost is justified, because the COX-2 drugs reduce the risk of gastrointestinal side effects.
But the Express Scripts' studies found that 74 percent of COX-2 users had no evidence of being at risk for gastrointestinal side effects. Other findings from the studies include:
The studies were based on data from a Midwest-based Preferred Provider Organization that included medical and pharmacy claims for new COX-2 users from Jan. 1, 2000, to May 31, 2000.
More information
If you doubt that more conventional pain medication can cause problems, read this piece about NSAIDs and peptic ulcers from the National Institute of Diabetes and Digestive and Kidney Diseases.