HealthDay operates under the strictest editorial standards. Our syndicated news content is completely independent of any financial interests, is based solely on industry-respected sources and the latest scientific research, and is carefully fact-checked by a team of industry experts to ensure accuracy.
- All articles are edited and checked for factual accuracy by our Editorial Team prior to being published.
- Unless otherwise noted, all articles focusing on new research are based on studies published in peer-reviewed journals or issued from independent and respected medical associations, academic groups and governmental organizations.
- Each article includes a link or reference to the original source.
- Any known potential conflicts of interest associated with a study or source are made clear to the reader.
Please see our Editorial and Fact-Checking Policy for more detail.Editorial and Fact-Checking Policy
HealthDay Editorial Commitment
HeathDay is committed to maintaining the highest possible levels of impartial editorial standards in the content that we present on our website. All of our articles are chosen independent of any financial interests. Editors and writers make all efforts to clarify any financial ties behind the studies on which we report.
TUESDAY, Sept. 22, 2015 (HealthDay News) -- The combination pill Lonsurf (trifluridine and tipiracil) has been approved by the U.S. Food and Drug Administration to treat advanced colon cancer for people who aren't responding to other treatments, the agency said Tuesday in a news release.
Colon cancer is the third most common cause of non-skin cancer in the United States, the FDA said, citing the U.S. National Cancer Institute. It's still the second most common cause of cancer death behind lung cancer, although rates have been declining, in part, due to increased screening for the disease.
Lonsurf was evaluated in clinical trials involving some 800 people with previously treated advanced colorectal cancer. Those who took Lonsurf lived an average of more than 7 months, compared to 5.3 months for those who took a placebo.
The drug's most common side effects include anemia, a drop in infection-fighting white blood cells, a drop in blood platelets, weakness, fatigue, nausea, loss of appetite, diarrhea, abdominal pain and fever.
Due to the potential for a severe drop in blood cell and platelet production, doctors are urged to test users' blood before the start of each treatment cycle, the FDA said. Doctors also are advised to warn women of childbearing age of potential harm to developing fetuses. And women who use Lonsurf should not breastfeed, the agency warned.
Lonsurf is produced by Princeton, N.J.-based Taiho Oncology.
The FDA has more about this approval.
This story may be outdated. We suggest some alternatives.
The content contained in this article is over two years old. As such our recommendation is that you reference the articles below for the latest updates on this topic. This article has been left on our site as a matter of historic record. Please contact us at email@example.com with any questions.