Measuring the Damage of Cancer

Identifies DNA damage caused by drugs, natural cell death

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FRIDAY, March 5, 2004 (HealthDayNews) -- The difference between DNA damage caused by cancer-fighting drugs and damage caused by natural cell death is outlined in a study in the March 5 online issue of Cytometry, Part A.

Researchers used cytometry measurement of a phosphorylated histone to detect and quantify DNA damage in individual cells.

DNA damage in the form of double-strand breaks can be caused by naturally occurring cell death, radiation, or anti-tumor drugs.

The ability to use multiparameter cytometry to determine what caused DNA damage could prove important in the future study and understanding of DNA damage and repair. That may be especially true in the context of cellular responses to environmental stress or therapy.

More information

The American Medical Association has more about genetics.

SOURCE: John Wiley & Sons Inc., news release, March 5, 2004

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