Obstructive Sleep Apnea Poses Cardiac Risk
Major cardiac events after percutaneous coronary intervention found in patients with obstructive sleep apnea
THURSDAY, Jan. 11 (HealthDay News) -- Obstructive sleep apnea may be a risk factor for major cardiac events after percutaneous coronary intervention in patients with acute coronary syndromes, researchers report in the Jan. 1 issue of the American Journal of Cardiology.
Dai Yumino, M.D., of Tokyo Women's Medical University in Japan, and colleagues performed a sleep study in 89 patients with acute coronary syndromes who were successfully treated with percutaneous coronary intervention, or PCI, to determine if obstructive sleep apnea affects PCI outcome.
Obstructive sleep apnea, defined as having an apnea hypopnea index of 10 or more per hour, was found in 57 percent of patients with acute coronary syndrome. Major adverse cardiac events, including cardiac death and reinfarction, were more frequent in patients with sleep apnea (23.5 percent versus 5.3 percent). Obstructive sleep apnea was found to be a significant independent predictor of these events (hazard ratio, 11.61).
"The present study showed a high prevalence of obstructive sleep apnea among patients with acute coronary syndrome," the authors write. "Moreover, obstructive sleep apnea appeared to be an independent predictor for clinical and angiographic outcomes after PCI."