HFSA: Heart-Failure Patients May Be Aspirin Resistant

Study of chest-pain patients finds a nearly doubled prevalence in those with heart failure

WEDNESDAY, Sept. 13 (HealthDay News) -- Heart-failure patients being treated in the emergency department may be more likely to have aspirin resistance than other patients, according to research presented this week at the Heart Failure Society of America's 10th annual scientific meeting, in Seattle.

Lori B. Daniels, M.D., of the University of California, San Diego, and colleagues tested for aspirin resistance in 516 patients who presented at an emergency department with chest pain, 25 percent of whom had a history of heart failure. All subjects were either on outpatient aspirin therapy or received an aspirin upon arrival.

The researchers found 20 percent of heart-failure patients had aspirin resistance compared to 12 percent of other patients.

"Resistance to aspirin is an increasingly recognized phenomenon which may have severe clinical sequelae," the authors wrote. "Aspirin resistance testing may be an important adjunct in the acute assessment of heart failure patients to help optimize anticoagulation therapies."

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