See What HealthDay Can Do For You
Contact Us

Diabetes Requiring Insulin Tied to Increased Stroke Risk in A-Fib

Patients requiring insulin, but not those without diabetes or without insulin, have increased risk

heart

WEDNESDAY, Jan. 25, 2017 (HealthDay News) -- For patients with atrial fibrillation (AF), diabetes requiring insulin, but not diabetes without insulin treatment, is associated with an increased risk of stroke/systemic embolism, according to a study published in the Jan. 31 issue of the Journal of the American College of Cardiology.

Giuseppe Patti, M.D., from the Campus Bio-Medico University of Rome, and colleagues examined the differential role of insulin versus no insulin therapy on thromboembolic risk in a cohort of patients with AF. The authors compared the rates of stroke/systemic embolism at one year according to diabetes status. Data were included for 5,717 patients; 1,288 of these had diabetes, of whom 22.4 percent were on insulin.

The researchers found that the risk of stroke/systemic embolism at one year was increased for patients with diabetes who were on insulin, compared to those without diabetes (5.2 versus 1.9 percent; hazard ratio, 2.89; 95 percent confidence interval, 1.67 to 5.02; P = 0.0002) or those with diabetes without insulin treatment (5.2 versus 1.8 percent; hazard ratio, 2.96; 95 percent confidence interval, 1.49 to 5.87; P = 0.0019). Similar rates of stroke/embolism were seen for patients with diabetes not receiving insulin and for patients without diabetes (hazard ratio, 0.97; 95 percent confidence interval, 0.58 to 1.61; P = 0.90).

"In this cohort of anticoagulated patients with AF, the sole presence of diabetes not requiring insulin did not imply an increased thromboembolic risk," the authors write. "Conversely, insulin-requiring diabetes contributed most, if not exclusively, to the overall increase of thromboembolic risk in AF."

Several authors disclosed financial ties to the pharmaceutical industry.

Full Text
Editorial

Physician's Briefing

HealthDay

HealthDay is the world’s largest syndicator of health news and content, and providers of custom health/medical content.

Consumer Health News

A health news feed, reviewing the latest and most topical health stories.

Professional News

A news feed for Health Care Professionals (HCPs), reviewing latest medical research and approvals.