APS: Diabetes, Depression Affect Heart Patient Outcomes

Researchers find elevated risk of death in heart patients who have both diabetes and depression

TUESDAY, March 13 (HealthDay News) -- In patients with established heart disease, two tandem conditions -- type 2 diabetes and depression -- can significantly increase the risk of mortality, according to research presented at the 65th Annual Scientific Conference of the American Psychosomatic Society in Budapest, Hungary.

Anastasia Georgiades, Ph.D., of Duke University in Durham, N.C., and colleagues studied 907 patients with coronary artery disease who underwent coronary angiography, including 325 patients who had diabetes. During a median three-year follow-up, 135 of the patients died.

The researchers found that diabetes and depression were independently associated with an increased risk of death. But the risk was highest in patients with both conditions. Patients with diabetes and high depression scores had a 20 percent to 30 percent higher risk of death compared to non-diabetics who also had high depression scores, the study authors report.

"There is some sort of synergistic effect between type 2 diabetes and depression that we don't fully understand," Georgiades said in a statement. "In our analysis, we controlled for factors that could influence mortality, such as heart disease severity and age. For whatever reasons, these patients were still at higher risk of dying, and future research will aim to investigate the mechanisms for this association."

Abstract #1789 (P. 55)

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