Atherothrombotic Patients Have Similar CVD Risk Factors

Risk factors largely under-treated and under-controlled in many parts of the world

TUESDAY, Jan. 10 (HealthDay News) -- Atherothrombotic patients in 44 countries have similar cardiovascular risk factors, including under-controlled and under-treated hypertension, high cholesterol and obesity, according to a study in the Jan. 11 issue of the Journal of the American Medical Association.

Deepak L. Bhatt, M.D., of The Cleveland Clinic Foundation in Ohio, and colleagues analyzed data from the Reduction of Atherothrombosis for Continued Health (REACH) Registry on 67,888 patients ages 45 or older from 44 countries: 40,258 with coronary artery disease; 18,843 with cerebrovascular disease; 8,273 with peripheral arterial disease; and 12,389 with three or more risk factors for atherothrombosis.

The researchers found a high prevalence of hypertension (81.8%), hypercholesterolemia (72.4%), diabetes (44.3%), overweight (39.8%), obesity (26.6%) and morbid obesity (3.6%). But they found the highest prevalence of overweight, obesity and morbid obesity in North America (37.1%, 36.5% and 5.8%, respectively). They also found that 50% of patients worldwide were under-treated for hypertension and were generally under-treated with statins (69.4%) and anti-platelet agents (78.6%).

"This large, international, contemporary database shows that classic cardiovascular risk factors are consistent and common, but are largely under-treated and under-controlled in many regions of the world," the authors write. The REACH Registry is sponsored by Sanofi-Aventis, Bristol-Myers Squibb and the Waksman Foundation.

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