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Out-of-Hospital CHD Mortality Higher in Young Men

May partly explain why young women hospitalized with MI have higher in-hospital mortality

FRIDAY, July 2 (HealthDay News) -- Young men have a higher rate of out-of-hospital coronary heart disease (CHD) mortality than young women, which could partly explain the fact that young women are more likely than young men to die when hospitalized for myocardial infarction (MI), according to research published in the July 1 issue of the American Journal of Cardiology.

Yu-Hsuan Shao, Ph.D., of the New Jersey Robert Wood Johnson Medical School in New Brunswick, and colleagues analyzed 1990-to-2004 data on 247,701 men and 175,366 women hospitalized with MI, and 355,569 patients who died of CHD.

The researchers found that, of patients hospitalized for MI, women ages 35 to 54 years of age had a higher in-hospital mortality rate than men in that age group (5.2 versus 2.5 percent). However, in a community-wide analysis involving an examination of total out-of-hospital CHD deaths in New Jersey, they found that young women had a lower out-of-hospital death rate than young men (11 versus 55 per 100,000). Statewide, young women were hospitalized four times less frequently for MI than young men (78 versus 297 per 100,000), but were only half as likely to die from MI in the hospital (7 versus 17 per 100,000).

"In conclusion, the greater in-hospital mortality of young women hospitalized for MI compared to young men could be explained in part by the finding that young men were more likely to have out-of-hospital CHD death," the authors write.

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