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Ventricular Dyssynchrony Predicts Remodeling

Predicts remodeling at six months with a high sensitivity and specificity

WEDNESDAY, Oct. 10 (HealthDay News) -- Left ventricular dyssynchrony measured soon after an acute myocardial infarction can predict left ventricular remodeling at six months with a high specificity and sensitivity, according to study findings published online Oct. 1 in the Journal of the American College of Cardiology.

Jeroen J. Bax, M.D., Ph.D., from Leiden University Medical Center in the Netherlands, and colleagues examined factors predicting left ventricular remodeling in 178 patients with acute myocardial infarction who underwent primary percutaneous coronary intervention.

The researchers found that 20 percent of patients underwent left ventricular remodeling at six months. As measured by speckle-tracking radial strain analysis, left ventricular dyssynchrony was a superior predictor of remodeling at six months, with a sensitivity of 82 percent and a specificity of 95 percent using a cutoff value of 130 ms.

"Left ventricular dyssynchrony immediately after acute myocardial infarction predicts left ventricular remodeling at six-month follow-up," Bax and colleagues conclude.

Abstract
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