Here are what the editors at HealthDay consider to be the most important developments in Cardiology for April 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Meeting Organizers Overlooking Qualified Female Scientists
FRIDAY, April 28, 2017 (HealthDay News) -- Invited speakers at medical conferences tend to be disproportionately male, a disparity that can be addressed by actively preparing lists of potential speakers, according to a study published online April 18 in Nature Immunology.
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Exercise Reduces Weight Gain Effects in Those With FTO Gene
FRIDAY, April 28, 2017 (HealthDay News) -- Eleven novel adiposity variants have been identified after adjustment for physical activity (PA), and PA can reduce the weight-gaining effects of the FTO gene by about 30 percent, according to a meta-analysis published online April 27 in PLOS Genetics.
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Plasma Catecholamines Predict Post-Op A-Fib After Cardiac Sx
FRIDAY, April 28, 2017 (HealthDay News) -- Assessment of plasma catecholamines on the morning of surgery can predict the likelihood of postoperative atrial fibrillation (POAF) for patients undergoing elective cardiac surgery, according to a study published online April 26 in the Journal of the American College of Cardiology.
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Routine Blood Tests Can Harm Patient Care
FRIDAY, April 28, 2017 (HealthDay News) -- Routine blood tests waste money and can damage patient care, according to an opinion piece published online April 27 in the BMJ.
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Risk Factors in Six Areas Tied to Physician Burnout
THURSDAY, April 27, 2017 (HealthDay News) -- Physician burnout factors include control, whether there is time to deliver excellent care, and whether the workplace is fair, according to a presentation at the Medical Group Management Association/American Medical Association 2017 Collaborate in Practice Conference, held April 9 to 11 in Chicago.
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Single-Payer Health System Bill Moves Forward in California
THURSDAY, April 27, 2017 (HealthDay News) -- A proposal to replace private insurance with government-funded health care for all moved forward in California on Wednesday as Democrats on the Senate Health Committee voted to advance the measure.
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Higher QT Interval After Energy Drink Consumption Vs. Caffeine
THURSDAY, April 27, 2017 (HealthDay News) -- Consumption of energy drinks is associated with significantly higher corrected QT interval and systolic blood pressure (BP) than consumption of caffeine alone, according to a study published online April 26 in the Journal of the American Heart Association.
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Molecular Autopsy IDs Causes of Sudden Arrhythmic Death
WEDNESDAY, April 26, 2017 (HealthDay News) -- Molecular autopsy for electrical disorder and cardiomyopathy genes identifies a modest but realistic yield in sudden arrhythmic death syndrome (SADS), according to a study published online April 24 in the Journal of the American College of Cardiology.
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Plasma Uric Acid Lowering Tied to Drop in Systolic BP in T1DM
WEDNESDAY, April 26, 2017 (HealthDay News) -- Lowering of plasma uric acid (PUA) with febuxostat (FBX) is associated with a modest reduction in systolic blood pressure (BP) in patients with type 1 diabetes mellitus (T1DM), according to a study published online April 13 in Diabetes.
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Post-Op hsTnT Linked to 30-Day Mortality After Noncardiac Sx
TUESDAY, April 25, 2017 (HealthDay News) -- Peak postoperative high-sensitivity troponin T (hsTnT) is associated with increased risk of 30-day mortality among patients undergoing noncardiac surgery, according to a study published online April 25 in the Journal of the American Medical Association.
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Use of HEART Score Has Limited Impact for Chest Pain in ER
TUESDAY, April 25, 2017 (HealthDay News) -- Use of the History, Electrocardiogram, Age, Risk factors, and initial Troponin (HEART) score is safe but has a limited effect on health care resource use among patients presenting at the emergency department with chest pain, according to a study published online April 24 in the Annals of Internal Medicine.
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Gut Bacteria May Convert Choline Into Clot-Enhancing Compound
TUESDAY, April 25, 2017 (HealthDay News) -- Consuming excess choline raises levels of the bacteria-produced compound trimethylamine N-oxide (TMAO) and increases the tendency of platelets to clump together and form clots, according to a study published online April 24 in Circulation.
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Central Obesity Ups Mortality Across BMI Range
TUESDAY, April 25, 2017 (HealthDay News) -- Central obesity is associated with increased risk of mortality even in normal-weight individuals, according to a study published online April 24 in the Annals of Internal Medicine.
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T2DM Risk Cut by Variant in Sulfonylurea Receptor Encoder
TUESDAY, April 25, 2017 (HealthDay News) -- A common missense variant in the gene encoding a component of the sulfonylurea receptor (ABCC8 p.A1369S), which promotes closure of the target channel of sulfonylurea therapy, mimicking the effects of therapy, is associated with reduced risk of type 2 diabetes and coronary heart disease, according to a study published online April 14 in Diabetes.
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Cycling To and From Work Linked Lower CVD, Mortality Risk
MONDAY, April 24, 2017 (HealthDay News) -- Biking to work may help lengthen lifespan, according to a study published online April 19 in The BMJ.
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NYC to Raise Cigarette Prices to Highest in the United States
FRIDAY, April 21, 2017 (HealthDay News) -- A proposal to boost the base price of a pack of cigarettes from $10.50 to $13.00 would make cigarettes in New York City the most expensive in the country.
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Wearable Devices Increasingly Being Used to Record Health Data
FRIDAY, April 21, 2017 (HealthDay News) -- Wearable devices are increasingly being used by patients to record health care data, and the number is expected to grow, according to an article published in Medical Economics.
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Early Glycemic Control With Metformin Cuts CVD Events
FRIDAY, April 21, 2017 (HealthDay News) -- For patients with type 2 diabetes who initiate metformin, early achievement of low hemoglobin A1c (HbA1c) is associated with a reduction in the subsequent risk of cardiovascular events or death, according to a study published online April 12 in Diabetes Care.
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Microvascular Endothelial Dysfunction Can Predict Dementia
FRIDAY, April 21, 2017 (HealthDay News) -- Markers of microvascular endothelial dysfunction can predict dementia, according to a study published online April 13 in the Journal of Internal Medicine.
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Vertical Integration Linked to Reduction in Readmissions
THURSDAY, April 20, 2017 (HealthDay News) -- Vertical integration, merging health care providers of different levels into a single unit, is associated with a reduction in readmissions overall, although the positive effect is seen for a limited number of conditions, according to a study published in the May issue of Medical Care.
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Artificially-Sweetened Drinks Linked to Stroke, Dementia Risk
THURSDAY, April 20, 2017 (HealthDay News) -- Consumption of artificially-sweetened drinks is associated with increased risk of stroke and dementia, according to a study published online April 20 in Stroke.
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Electronic Drug Administration Record App Cuts Errors
THURSDAY, April 20, 2017 (HealthDay News) -- Use of an electronic medication administration record (eMAR) application can reduce the rate of medication errors in medication administration recording (ME-MAR), according to a study published online April 18 in the Journal of Evaluation in Clinical Practice.
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Just Over Half of MI Patients Taking Statins As Recommended
THURSDAY, April 20, 2017 (HealthDay News) -- Many myocardial infarction patients aren't taking statins as recommended, according to a brief report published online April 19 in JAMA Cardiology.
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Chagas Disease Presents Public Health Challenge in the U.S.
WEDNESDAY, April 19, 2017 (HealthDay News) -- Chagas disease, caused by the parasite Trypanosoma cruzi and transmitted by the triatomine bug, is a public health concern in the United States, according to the Drugs for Neglected Diseases Initiative (DNDi).
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Potential Benefits, Risks of OpenNotes Discussed
WEDNESDAY, April 19, 2017 (HealthDay News) -- The benefits of sharing notes with patients include improved patient engagement and empowerment, while potential risks may include more phone calls, questions, and increased documentation time, according to a report published in Medical Economics.
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Review: Interventions Don't Promote Exercise in Rural Adults
WEDNESDAY, April 19, 2017 (HealthDay News) -- Interventions to promote physical activity (PA) among adults have no effect in rural communities, according to a review published online April 11 in Obesity Reviews.
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Single hs-cTnT Measure, Non-Ischemic ECG Can Rule Out AMI
WEDNESDAY, April 19, 2017 (HealthDay News) -- For adults presenting to the emergency department with chest pain, a single high-sensitivity assay for cardiac troponin T (hs-cTnT) below the limit of detection and a non-ischemic electrocardiogram (ECG) can rule out acute myocardial infarction (AMI), according to a meta-analysis published online April 18 in the Annals of Internal Medicine.
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LVAD Can Restore Full Cardiac Function in Heart Failure Patients
WEDNESDAY, April 19, 2017 (HealthDay News) -- Battery-operated left ventricular assist devices (LVADs) may restore cardiac function for some heart failure patients, according to a study published in the April 18 issue of the Journal of the American College of Cardiology.
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No Proof Azithromycin Ups Odds of Ventricular Arrhythmia
TUESDAY, April 18, 2017 (HealthDay News) -- Azithromycin doesn't appear to increase the risk of ventricular arrhythmia, according to a study published online April 18 in CMAJ, the journal of the Canadian Medical Association.
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Differing Statin Guidelines Leave Many Clinicians Uncertain
TUESDAY, April 18, 2017 (HealthDay News) -- If all clinicians followed U.S. Preventive Services Task Force (USPSTF) guidelines for prescription of a statin, nine million fewer adults would be taking such medication versus adherence to the American College of Cardiology/American Heart Association recommendations, according to a study published in the April 18 issue of the Journal of the American Medical Association.
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Glucose Variation Doesn't Affect Microvascular Complications
TUESDAY, April 18, 2017 (HealthDay News) -- Measures of glycemic variability in type 1 diabetes, based on complete quarterly 7-point glucose profiles, fail to provide evidence that glycemic variability contributes to the risk of development or progression of microvascular complications beyond the influence of mean glucose levels, according to a study published online April 12 in Diabetes Care.
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Over 20 Percent of Maternal Mortality in Illinois Due to CVD
TUESDAY, April 18, 2017 (HealthDay News) -- More than one in five maternal deaths in Illinois in 2002 to 2011 were attributable to cardiovascular disease, according to a study published in the May issue of Obstetrics & Gynecology.
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Costs Up With Specialist As Predominant Provider of Care
TUESDAY, April 18, 2017 (HealthDay News) -- For older adults with multimorbidity, having a specialist as the predominant provider of care (PPC) is associated with higher spending and lower continuity of care, according to a study published online April 8 in the Journal of the American Geriatrics Society.
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Pre-Op Training Program Improves Outcomes
TUESDAY, April 18, 2017 (HealthDay News) -- A home-based, preoperative training program can decrease hospital duration of stay and costs of care, while being well accepted by patients, according to a study published recently in Surgery.
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Doctors Need to Be Mindful of What They Post on Social Media
MONDAY, April 17, 2017 (HealthDay News) -- Young doctors often have unprofessional or offensive content on their Facebook profiles, according to a study published online April 9 in BJU International.
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Vitamin B May Help Mitigate Health Risks From Air Pollution
MONDAY, April 17, 2017 (HealthDay News) -- While exposure to concentrated air pollution has a negative effect on heart rate and levels of white blood cells, these effects are nearly reversed with four-week vitamin B supplementation, according to a study published online April 3 in Scientific Reports.
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Moderate, High-Intensity Exercise Programs Show Similar Results
MONDAY, April 17, 2017 (HealthDay News) -- Short-term moderate-intensity to high-intensity interval training (HIIT) leads to modest body composition improvements in overweight and obese individuals, according to research published online April 11 in Obesity Reviews.
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Major Bleeding Risk From Drugs Similar in Elderly
MONDAY, April 17, 2017 (HealthDay News) -- The risk of major bleeding is similar for older patients with atrial fibrillation taking either antiplatelet or anticoagulant drugs, according to a review published online April 10 in the Journal of Thrombosis and Haemostasis.
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Early Invasive Doesn't Beat Selective Strategy in NSTE-ACS
MONDAY, April 17, 2017 (HealthDay News) -- An early invasive strategy has no benefit for reducing the 10-year composite outcomes of death or spontaneous myocardial infarction (MI) for patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) and elevated cardiac troponin T, according to a study published in the April 18 issue of the Journal of the American College of Cardiology.
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Hot Flashes in Early Menopause May Indicate Elevated CVD Risk
FRIDAY, April 14, 2017 (HealthDay News) -- Hot flashes may signal increased risk of vascular dysfunction that can lead to cardiovascular disease, according to a study published online April 12 in Menopause.
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Reduced Glomerular Filtration Rate Major Cause of CV Deaths
FRIDAY, April 14, 2017 (HealthDay News) -- Kidney disease is a major cause of cardiovascular deaths worldwide, according to a study published online April 13 in the Journal of the American Society of Nephrology.
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High Readmission Rates for Critical Limb Ischemia
FRIDAY, April 14, 2017 (HealthDay News) -- Patients with critical limb ischemia (CLI) have a high risk of readmission, with most of the readmissions unplanned, according to a study published in the April 18 issue of the Journal of the American College of Cardiology.
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Favorable Physiological Effect for Ularitide in Acute Heart Failure
THURSDAY, April 13, 2017 (HealthDay News) -- Ularitide has a favorable physiological effect in patients with acute heart failure, according to a study published online April 12 in the New England Journal of Medicine.
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Accurate Diagnosis of Endocrine Hypertension Important
THURSDAY, April 13, 2017 (HealthDay News) -- An accurate diagnosis of endocrine hypertension allows clinicians to provide effective treatment, including a surgical cure or to achieve an optimal response with specific pharmacologic therapy, according to a scientific statement published online April 5 in Endocrine Reviews.
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Delays in Emergency Care Up Mortality During Major Marathons
THURSDAY, April 13, 2017 (HealthDay News) -- Nearby residents appear more likely to die from acute myocardial infarction and cardiac arrest during a marathon, according to research published in the April 13 issue of the New England Journal of Medicine.
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6 Variables Can Predict Mortality Risk in Cardiogenic Shock
THURSDAY, April 13, 2017 (HealthDay News) -- Six variables can be combined to predict short-term mortality risk in patients with cardiogenic shock (CS), according to a study published in the April 18 issue of the Journal of the American College of Cardiology.
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Physicians Are Spending Half Their Time on Computer Tasks
WEDNESDAY, April 12, 2017 (HealthDay News) -- Physicians spend roughly as many hours on computer work as they do meeting with patients, according to a study published in the April issue of Health Affairs.
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Midlife Vascular Risk Factors Associated With Elevated Amyloid
WEDNESDAY, April 12, 2017 (HealthDay News) -- Individuals with risk factors for cardiovascular disease and stroke in middle age are more likely to have elevated levels of amyloid, according to a study published in the April 11 issue of the Journal of the American Medical Association.
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AHA: Patients Lack Confidence in Managing Their Cholesterol
TUESDAY, April 11, 2017 (HealthDay News) -- Many patients report lack of confidence or knowledge in keeping cholesterol under control, a new American Heart Association survey shows.
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Cross-Sex Hormones Appear to Be Safe for Transgender Teens
TUESDAY, April 11, 2017 (HealthDay News) -- Cross-sex hormones appear to be safe for transgender adolescents, according to a study published online April 6 in Pediatrics.
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Acute Ischemic Stroke Prevalence Up in Younger Americans
TUESDAY, April 11, 2017 (HealthDay News) -- Acute ischemic stroke is increasingly prevalent in Americans under 65, as is the percentage of those with three or more stroke risk factors, according to a study published online April 10 in JAMA Neurology.
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Race Affects Obesity-Related Risk of Adolescent Hypertension
TUESDAY, April 11, 2017 (HealthDay News) -- Obese teenagers are at increased risk of hypertension, but the effects of those extra pounds may vary by race and ethnicity, according to a study published online April 10 in Pediatrics.
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Integrated E-Prescribing Can Cut Prescribing, Dispensing Errors
MONDAY, April 10, 2017 (HealthDay News) -- An integrated electronic medication prescribing (e-prescribing) and dispensing system can reduce prescribing and dispensing errors, according to a study published online March 30 in the Journal of Pharmacy Practice and Research.
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Exercise Capacity Prognostically Beneficial for Patients
MONDAY, April 10, 2017 (HealthDay News) -- Cardiopulmonary exercise testing, unless contraindicated, should be performed to obtain an overall view of cardiac and pulmonary patients' clinical status, according to a review published online March 31 in the Annals of the American Thoracic Society.
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Lower Risk of Gastrointestinal Bleeding for Apixaban
MONDAY, April 10, 2017 (HealthDay News) -- For patients receiving direct oral anticoagulant (DOAC) agents for non-valvular atrial fibrillation, apixaban is associated with a lower risk of gastrointestinal (GI) bleeding than rivaroxaban or dabigatran, according to a study published in the April issue of Gastroenterology.
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Multivitamin Use Does Not Benefit Cardiovascular Health in Men
FRIDAY, April 7, 2017 (HealthDay News) -- A daily multivitamin doesn't benefit cardiovascular health in men, according to a study published online April 5 in JAMA Cardiology.
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MACRA Changes Government Approach to Doctor Payment
FRIDAY, April 7, 2017 (HealthDay News) -- Implementation of the Medicare Access and CHIP Reauthorization Act (MACRA) has made fundamental changes to the government's approach to physician payment, according to a March 27 policy brief published in Health Affairs.
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991 Used Oregon's Physician-Aided Dying Law 1998 to 2015
FRIDAY, April 7, 2017 (HealthDay News) -- Fewer than 1,000 residents have followed through since Oregon became the first state to permit physician-aided dying in 1997, according to a report published online April 6 in JAMA Oncology.
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Cardiorespiratory Fitness Impacts BMI-Related Heart Failure Risk
THURSDAY, April 6, 2017 (HealthDay News) -- Higher body mass index (BMI) is associated with increased risk of heart failure, which is largely explained by differences in cardiorespiratory fitness (CRF), according to a study published online April 5 in JACC: Heart Failure.
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Risk Adjustment, Reinsurance Transfer Offer Financial Benefit
THURSDAY, April 6, 2017 (HealthDay News) -- Risk adjustment and reinsurance transfer programs seem to have been effective for increasing revenues at the expense of claims costs, according to research published in the March issue of Health Affairs.
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Autoantibodies to GPIHBP1 Identified in Chylomicronemia
THURSDAY, April 6, 2017 (HealthDay News) -- Some patients with chylomicronemia have autoantibodies to glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 (GPIHBP1), causing severe hypertriglyceridemia, according to a study published online April 5 in the New England Journal of Medicine.
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Pre-Stroke Fitness, but Not BMI, May Predict Post-Stoke Disability
THURSDAY, April 6, 2017 (HealthDay News) -- Stroke patients who are active and exercise regularly before the event have a lower risk of post-stroke disability, but body mass index does not appear to be related to the decreased risk, according to a study published online April 5 in Neurology.
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Stem Cell-Sheet Transplantation Feasible in Cardiomyopathy
THURSDAY, April 6, 2017 (HealthDay News) -- Stem cell-sheet transplantation shows promise in the treatment of cardiomyopathy, according to research published online April 5 in the Journal of the American Heart Association.
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No CVD Protection Seen With Monthly High-Dose Vitamin D
THURSDAY, April 6, 2017 (HealthDay News) -- Taking high doses of vitamin D once a month won't lower the risk for cardiovascular disease, according to a study published online April 5 in JAMA Cardiology.
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Higher Risk of Cardiovascular Events With Weight Fluctuations
THURSDAY, April 6, 2017 (HealthDay News) -- Fluctuation in body weight is associated with higher mortality and a higher rate of cardiovascular events -- independent of traditional cardiovascular risk factors -- in patients with coronary artery disease, according to a study published in the April 6 issue of the New England Journal of Medicine.
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Second Opinion Yields Different Diagnosis for 1 in 5 Patients
WEDNESDAY, April 5, 2017 (HealthDay News) -- One-fifth of patients who sought a second opinion recently at a single academic medical center had received a different diagnosis from their primary care providers, according to a study published online April 4 in the Journal of Evaluation in Clinical Practice.
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Doctors Must Be Wary of HIPAA Violations With Online Reviews
TUESDAY, April 4, 2017 (HealthDay News) -- Physicians should be aware that responding to a negative health care review could potentially expose personal medical information, resulting in a Health Insurance Portability and Accountability Act (HIPAA) violation, according to an article published in Medical Economics.
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Maximum BMI Over 16 Years Ups Risk of All-Cause Death
TUESDAY, April 4, 2017 (HealthDay News) -- Maximum body mass index (BMI) over 16 years of weight history is associated with increased risk of all-cause death, according to a study published online April 4 in the Annals of Internal Medicine.
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Firefighters Exhibit Increased Cardiovascular Impairment
MONDAY, April 3, 2017 (HealthDay News) -- Exposure to fire is associated with activation of platelets, increased thrombus formation, and impaired vascular function, promoting myocardial ischemia and injury, according to a study published in the April 4 issue of Circulation.
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Use of Health Literacy Tools Can Promote Shared Decision Making
MONDAY, April 3, 2017 (HealthDay News) -- Use of health literacy tools is encouraged for facilitating shared decision making (SDM), according to an article published in the March issue of the AMA Journal of Ethics.
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MRI Measures Can Predict Pulmonary Arterial HTN Outcome
MONDAY, April 3, 2017 (HealthDay News) -- Magnetic resonance imaging (MRI) measures can predict outcomes in pulmonary arterial hypertension (PAH), according to a study published online March 22 in the American Journal of Respiratory and Critical Care Medicine.
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Adding Defibrillator to CRT No Benefit in Dilated Cardiomyopathy
MONDAY, April 3, 2017 (HealthDay News) -- For patients with heart failure with indications for cardiac resynchronization therapy (CRT), those with ischemic cardiomyopathy (ICM), but not those with nonischemic dilated cardiomyopathy (DCM), benefit from additional primary prevention implantable cardioverter-defibrillator therapy, according to a study published in the April 4 issue of the Journal of the American College of Cardiology.
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Twenty-Five Food Categories Explain 70 Percent of Salt Intake
MONDAY, April 3, 2017 (HealthDay News) -- For U.S. persons, 70 percent of dietary sodium comes from 25 food categories, with bread the top contributor, according to research published in the March 31 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
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ANGPTL3 Deficiency Linked to Reduced CAD Risk
MONDAY, April 3, 2017 (HealthDay News) -- Angiopoietin-like 3 (ANGPTL3) deficiency is associated with reduced risk of coronary artery disease (CAD), according to a study published online March 29 in the Journal of the American College of Cardiology.
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