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Diabetes Lowers Women's Long-Term Survival Post-MI

Men's long-term mortality risk after MI less affected by diabetes status

WEDNESDAY, Dec. 22 (HealthDay News) -- Women with diabetes mellitus (DM) have a more than 2.5-fold long-term increased mortality rate after their first myocardial infarction (MI) compared to their counterparts without DM, according to a study published in the Dec. 15 issue of The American Journal of Cardiology.

Christa Meisinger, M.D., of the Central Hospital of Augsburg in Germany, and colleagues compared the short- and long-term mortality rates of men and women, with and without DM, following a first MI. They analyzed records from a population-based MI registry of 505 men and 196 women with DM and 1,327 men and 415 women without DM, who had a first MI between January 1998 and December 2003. They followed the outcomes of these patients until December 2005.

The researchers found that women with DM had a more than 2.5-fold higher risk for mortality in the long term (28 days following a first acute MI), than their counterparts without DM. Men with DM were found to have a borderline greater risk for long-term mortality, following a multi-variable adjustment of the data. Though the mortality rates were relatively high, a link between men and women with DM and death within the first 28 days following a first MI was not found to be statistically significant.

"Short-term mortality was not significantly increased in men and women with DM after a first-ever acute MI, although estimates were relatively high, indicating a possible relation. However, long-term mortality was higher in patients with acute MI and DM, particularly in women," the authors write.

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