Obese Have Lower Post-Angioplasty Mortality

Younger age offsets increased risk from comorbid conditions after myocardial infarction treatment

WEDNESDAY, April 4 (HealthDay News) -- Obese patients with acute myocardial infarction who undergo percutaneous coronary intervention are at lower risk for in-hospital, six-month and 12-month mortality and cardiovascular events than leaner patients, according to a report in the April 1 issue of the American Journal of Cardiology. Obese patients tend to be younger and may receive more aggressive treatment than average-weight patients.

Laxmi Mehta, M.D., of the William Beaumont Hospital in Royal Oak, Mich., and colleagues analyzed data on 2,325 patients with acute myocardial infarction who underwent percutaneous coronary intervention, of whom 70 percent were classified as overweight or obese. Obese patients were younger, and more frequently had comorbid conditions such as diabetes, hypertension or hyperlipidemia.

The strongest predictors of 12-month mortality were age above 70 years, final Thrombosis In Myocardial Infarction grade below 3 flow, ejection fraction and peripheral vascular disease. The authors point to age as the major confounding factor in the study findings.

"This implies that acute myocardial infarction occurs at a younger age in the obese, and it is this younger age that counterbalances the risks that diabetes and hypertension pose in the immediate course of care," the authors conclude. "As part of being younger, obese patients may have received more aggressive or attentive care. Conversely, older patients, more likely to be in the normal body mass index group, may not have fared as well in the treatment provided."

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