Hemophilia News

Hemophilia is a rare blood disorder in which blood doesn’t clot normally because of a lack of clotting factor, a blood protein. Individuals with hemophilia don’t bleed any faster than others, but they often bleed for a longer amount of time.

Hemophilia doesn’t occur very often, and about one in every 10,000 people are born with the disease. There are two types, hemophilia A and hemophilia B, that each refer to the lack of a different type of clotting factor. But the disease often presents the same way in people with either type of hemophilia.

Causes

In the vast majority of cases, hemophilia is a hereditary disease that is passed down from parents to children. In very rare instances, it can be acquired at some point during your lifetime. When the average person begins bleeding, the platelets in the blood start to stick together with the help of clotting factor to plug the hole and stop the bleeding. But individuals with hemophilia have little or no clotting factor, so the bleeding continues even after it should stop. This can range from mild to severe in nature, and hemophilia can be quite dangerous if left untreated.

Treatment

The primary treatment for hemophilia is known as replacement therapy. Essentially, this is a therapy administered by an IV or injection that replaces the missing clotting factor in the body with new clotting factor. This can be done periodically as a preventive measure, or only periodically as the individual needs it.

There are other treatments for hemophilia, as well. For example, certain hormonal therapies can release stores of clotting factor that are already in the body, and there are also drugs often given along with replacement therapy that help prevent blood clots from breaking down.

SOURCES: World Federation of Hemophilia; National Institutes of Health: National Heart, Lung, and Blood Institute.

Date Posted
Article Title
11/16/2017
8/3/2017
Engineered Skin Cells Control Type 2 Diabetes in Mice: Study

'Therapeutic skin grafts' might someday treat multiple diseases, researchers say

12/29/2016
Researchers Develop Potential Oral Treatment for Hemophilia

Currently, genetic bleeding disorder is treated with injections

12/6/2016
Gene Therapy Offers Hope to Some Hemophilia Patients

Small, preliminary trial suggests it may free hemophilia B patients from transfusions

5/25/2016
2 New Findings Offer Hope for Those With Severe Hemophilia

One pinpoints when standard therapy works best, while the other uncovers the promise of a new drug

3/16/2016
Review Finds Mixed Success With Hemophilia Treatment

Researchers surprised by shortcomings in treatment of men with severe forms of the blood-clotting disorder

7/31/2015
Kids' Hemophilia Drugs a Big Part of State Medicaid Spending

California-based study finds drugs for the blood disorder take up large share of budget

10/24/2014
New Treatment Approved for Rare Form of Hemophilia

The bleeding disorder affects both males and females

6/9/2014
3/31/2014
Long-Acting Clotting Agent Approved for Form of Hemophilia

Alprolix requires less frequent injections

12/23/2013
Tretten Approved for Genetic Clotting Disorder

Rare condition could be life threatening

6/27/2013
10/9/2012
Kids With Hemophilia Should Be Active, But Avoid Risky Sports: Study

Non-contact activities safest, allowing children to enjoy exercise, experts say

12/12/2011
Gene Therapy a Boon for 6 Hemophilia Patients

Severity of the bleeding condition was reduced for men with type B disorder, study finds

11/2/2011
Using Drug for Prevention Might Help in Hard-to-Treat Hemophilia

For some patients, using medicine to stave off, not just treat bleeds, could decrease joint damage

4/19/2011
Off-Label Use of Clotting Drug Soars, Report Finds

Stanford researchers question use of expensive drug for other medical treatments despite risk

2/18/2011
1/27/2011
Health Tip: Possible Complications of Hemophilia

The blood disorder can lead to additional problems

11/4/2010
Hemophilia Drug Used Off-Label Raises Clot Risk

Those without blood disorder who were given it were twice as likely to have trouble, review found

6/16/2009
Strides Made in Hemophilia Research

Successful blood-clotting in lab could pave way for human trials, researchers say

10/10/2008
Kogenate FS Prevents Joint Damage in Young Hemophiliacs

Hemophilia A affects about 15,000 in the U.S.

2/21/2008
Hemophilia Treatment Approved

Xyntha supplements affected blood factor

2/14/2008
Transplanted Liver Lining Cells May Cure Hemophilia

Experiments in mice may lead to new treatments for the disease, study suggests

8/17/2006
Health Tip: Hemophiliacs, Be Cautious

Protect yourself from injury

1/11/2006
Polymer Aids in Blood Clotting

Finding could lead to new treatment for diseases like hemophilia, study says

7/31/2003
The Bright Side of a Genetic Disease

Mothers of hemophiliacs have lower death rate

7/29/2003
New Clotting Factor for Hemophiliacs

Eliminates possible germ transmission

6/13/2003
Pinpointing Clotting Problems

New test quickly measures thrombin in blood

5/16/2003
Hemophilia Drug May Have Wider Use

But there's disagreement over determining correct dosage

6/8/2002
New Type of Gene Therapy May Help Treat Hemophilia A

Technique shows promise in lab mice

1/1/2002
An Unhappy Christmas Story

British boy is namesake for hemophilia B

6/6/2001
Gene Therapy for Hemophilia Passes Test

Altered cells may correct genetic flaw