Clinical Trials Update: April 20, 2007

Obesity Liver Transplantation or Hepatitis B Colorectal Cancer

(HealthDay News) -- Here are the latest clinical trials, courtesy of Thomson CenterWatch:


If you are overweight but generally in good health, you may be eligible for a research study into obesity treatment.

Volunteers between ages 18 and 50 who are healthy non-smokers and able to complete up to four two-night stays at the research center may qualify. Compensation up to $2,000 is available for time and participation to those who complete the study.

The research site is in Portland, Ore.

More information

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Liver Transplantation or Hepatitis B

This is a study to evaluate the drug entecavir in subjects receiving a liver transplant because of chronic hepatitis B virus infection.

Successful candidates should be at least 18-years-old and are orthotopic liver transplant (OLT) patients with end-stage liver disease caused by chronic HBV infection.

Candidates will be restricted from this study if they are pregnant, breastfeeding or intend to become pregnant during the study, or are multi-organ or retransplant recipients.

The research site is in New York City.

Please see


Colorectal Cancer

This clinical study to determine the effectiveness of a new treatment in patients with metastatic colorectal cancer who have failed treatment with an oxaliplatin and fluoropyrimidine containing regimen.

Volunteers 18-years-old or older with histologically confirmed colorectal cancer who have failed therapy with an oxaliplatin and fluropyrimidine containing regimen may be included.

Disqualifications include previous therapy with VEGFR or EGFR inhibitor (prior monoclonal antibody is permitted); previous therapy with irinotecan within 12 months of randomization; any recent surgery, unhealed surgical incision or severe concomitant condition.

The research sites are in Tennessee, Michigan and New York.

More information

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