Clinical Trials Update: June 23, 2005
Colon Cancer Screening Systemic Lupus Erythematosus Malignant Melanoma
(HealthDay News) -- Here are the latest clinical trials, courtesy of CenterWatch:
Colon Cancer Screening
Most colon cancers develop from abnormal growths called polyps. Screenings to detect and remove polyps early are the number one way to prevent colon cancer and save lives. Adults 50 or older who are scheduled for a screening colonoscopy and have not received one in the past five years are eligible to participate in this study. Research sites located throughout the United States.
Systemic Lupus Erythematosus
This research study, which will last for approximately 18 months, will evaluate the impact of an investigational drug on patients with active systemic lupus erythematosus (SLE). This investigational drug study is intended for patients with moderate to severe SLE and who are taking methotrexate, azathioprine (Imuran), or mycophenolate mofetil (CellCept). Research site located in Lake Success, New York.
The purpose of this study is to determine the safety and efficacy of MDX-010 (anti-CTLA4) in combination with MDX-1379 in patients with previously treated, unresectable Stage III or IV melanoma. Survival time will be evaluated, as well as patient responses and time to disease progression. Participants must be at least 18 years old, diagnosed with measurable unresectable Stage III or IV melanoma, HLA-A*0201 positive and have previous treatment with & failure/relapse/inability to tolerate IL-2, dacarbazine and/or temozolomide. Research sites located throughout the United States.
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