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Clinical Trials Update: June 29 2005

Colon cancer; rectal cancer Healthy Patient Studies Kidney Failure

(HealthDay News) -- Here are the latest clinical trials, courtesy of CenterWatch:

Colon cancer; rectal cancer

This study will evaluate the efficacy and safety of Avastin in combination with a standard chemotherapeutic regimen as first-line treatment in patients with metastatic colon or rectal cancer. Participants must be adult patients at least 18 years of age, recently diagnosed metastatic cancer of the colon or rectum, no prior systemic treatment for the metastatic disease, and prior adjuvant treatment completed at least six months prior to treatment. Research sites located throughout Australia, Canada, Italy and Spain.

More Information

Please see http://www.centerwatch.com/patient/studies/cat684.html.

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Healthy Patient Studies

Recent research suggests that a simple blood test may show inflammation of the arteries, which may be an early indication of cardiovascular disease, even in people with normal or low cholesterol. This research trial will evaluate if an investigational drug will lower the risk of heart attack or stroke. Qualifications for the study include men 55 years old or older, women 65 years or older, and no previous history of heart attack or stroke. Research site located Sugar Land, Texas.

More Information

Please see http://www.centerwatch.com/patient/studies/phasei.html.

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Kidney Failure

This is a 400 mg sorafenib single-dose, open-label study being conducted to compare the pharmacokinetics of plasma and urine and safety of sorafenib in people with renal impairment with those exhibiting normal renal function. Participants must be post menopausal, surgically sterile females, and have body mass index between 18-37. Research sites located in Florida, Louisiana and Texas.

More Information

Please see http://www.centerwatch.com/patient/studies/cat456.html.

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Copyright 2005 CenterWatch. All rights reserved.

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