(HealthDay News) -- Here are the latest clinical trials, courtesy of Thomson CenterWatch:
Irritable Bowel Syndrome (IBS)
This study will evaluate the safety and effectiveness of an investigational drug to treat diarrhea-predominant irritable bowel syndrome (IBS). Women at least 18 with diarrhea-predominant IBS who have had an endoscopic and/or radiologic bowel evaluation within five years, or who are willing to have a new evaluation performed, may qualify. Participants may not be pregnant or breast feeding, or have any serious medical or surgical condition including colon cancer, Crohn's disease or ulcerative colitis.
The research sites are located across the United States.
More information
Please see http://www.centerwatch.com/patient/studies/cat90.html.
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Coronary Artery Disease
The clinical study will evaluate the effectiveness of a combination of ezetimibe and simvastatin over at least 2.5 years among high-risk coronary artery disease patients. A candidate will be eligible if his/her LDL-C concentration is between 50 and 125 mg/dL and he/she is not getting chronic statin therapy. A person receiving chronic statin therapy will be eligible if his/her LDL-C concentration is between 50 and 100 mg/dL.
The research site is in Miami, Fla.
More information
Please see http://www.centerwatch.com/patient/studies/cat50.html.
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Hypertension (High Blood Pressure)
This study will evaluate whether the study drug is effective among people who have resistant systolic hypertension, despite having been treated with full doses of four or more antihypertensive drugs, including a diuretic. Volunteers must have resistant systolic hypertension, and be receiving and adhering to full doses of an appropriate guideline-recommended antihypertensive drug regimen for a minimum of four weeks prior to the first study visit.
The research site is in Miami, Fla.
More information
Please see http://www.centerwatch.com/patient/studies/cat85.html.
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