Clinical Trials Update: Sept. 12, 2006

Healthy Patient Studies Hypertension (High Blood Pressure) Chronic Back Pain

(HealthDay News) -- Here are the latest clinical trials, courtesy of Thomson CenterWatch:

Healthy Patient Studies

This study will test the effect of vestibular stimulation on transient insomnia induced by a four-hour phase advance of sleep time.

Adults between the ages of 21 and 60 with regular sleep patterns who sleep 6.5 to 8.5 hours a night and do not currently work rotating or evening shifts may be included.

Participants will undergo an initial screening visit, an overnight sleep study and a day of sleep testing in the Sleep Disorders Center to determine eligibility for an investigational device designed to affect the time it takes to fall asleep.

Study subjects will return to test the investigational device for two nights and one day in the Sleep Disorders Center.

The research site is in Boston.

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Hypertension (High Blood Pressure)

The CORAL trial is a study of persons who have high blood pressure and narrowing of one or more of the blood vessels that supply the kidneys, called renal artery stenosis.

The study is designed to see whether using a stent to help open the narrowed blood vessel(s) will improve the patient's health as compared to careful treatment of high blood pressure and other cardiovascular risk factors (such as high cholesterol, smoking and diabetes) without stenting.

Adult patients with renal artery stenosis may be eligible to participate.

Patients will be seen in clinic for up to five years for follow up, and will be compensated for certain travel expenses.

The research site is in Charlottesville, Va.

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Chronic Back Pain

If you have chronic low back pain, you may be eligible for a research study of an investigational pain medication.

Study participants between the ages of 21 and 75 with a diagnosis of chronic low back pain who are currently taking pain medication for the condition may qualify.

The research site is in Denver, Colo.

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