Data Conflict on Link Between Inflammation, Pain in Knee OA

Conflicting data link inflammation and knee pain in knee osteoarthritis. In a systematic review of 37 studies, moderate levels of evidence supported a link between synovitis and pain; conflicting evidence linked effusion, effusion/synovitis, Baker’s cyst, cytokines, and C-reactive protein with pain.

Via Osteoarthritis and Cartilage. Published online December 27, 2021.