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Survival Benefit Seen with Extracorporeal CPR

Modest advantage seen versus traditional cardiopulmonary resuscitation following in-hospital cardiac arrest

MONDAY, July 7 (HealthDay News) -- Extracorporeal cardiopulmonary resuscitation (CPR) was associated with improved survival rates at discharge, one month and one year following in-hospital cardiac arrest, according to an article published online July 7 in The Lancet.

Yih-Sharng Chen, M.D., of the National Taiwan University Hospital in Taipei, Taiwan, and colleagues performed a three-year prospective observational study on the effect of extracorporeal CPR compared to traditional CPR for patients experiencing an in-hospital cardiac arrest requiring more than 10 minutes of CPR. Propensity-based scoring methods were used to control for confounders and to formulate a balanced 1:1 matched cohort study.

Of the 975 patients experiencing in-hospital cardiac arrest, 113 received conventional CPR and 59 received extracorporeal CPR, the report indicates. There was significant difference seen in survival to discharge for those receiving extracorporeal CPR versus CPR (hazard ratio, 0.51), as well as for 30-day and one-year survival (HRs, 0.47 and 0.53, respectively).

"Extracorporeal CPR might be recommended for adult in-hospital cardiac arrest patients of cardiac origin who have undergone CPR for more than 10 minutes and could provide a short-term and long-term survival advantage," according to the authors. "Further studies will be needed to identify potential subgroups in in-hospital cardiac arrest patients who could benefit from extracorporeal CPR."

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