Premature AMI Mortality Declined From 1999 to 2019

Decline slowed since 2011; was higher among large and medium/small metros versus rural counties

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THURSDAY, Dec. 23, 2021 (HealthDay News) -- During 1999 to 2019, there was a decline in premature mortality attributable to acute myocardial infarction (AMI), according to a study published online Dec. 22 in the Journal of the American Heart Association.

Sourbha S. Dani, M.D., from Beth Israel Lahey Health in Burlington, Massachusetts, and colleagues examined premature (younger than 65 years of age) age-adjusted AMI mortality rates per 100,000 using the U.S. Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research death certificate database and assessed the average annual percentage change from 1999 to 2019.

The researchers found that the age-adjusted AMI mortality rate was 13.4 per 100,000 overall. Compared with young adults, women, non-Hispanic White adults, and urban counties, higher mortality was seen among middle-aged adults, men, non-Hispanic Black adults, and rural counties, respectively. The age-adjusted AMI mortality rate decreased at an average annual percentage change of −3.4 percent per year between 1999 and 2019; the average annual percentage change showed a higher decline among large and medium/small metros versus rural counties (−4.2 and −3.3 per year, respectively, versus −2.4 per year). After an initial decline between 1999 and 2011 (−4.3 per year), there was a deceleration in the average annual percentage change in mortality since 2011 (−2.1 per year). Across both sexes, all ethnicities and races, and urban/rural counties, these trends were consistent.

"These findings have sizeable public health implications regarding identifying clinical differences and social vulnerabilities in critical demographic subgroups and geographic hotspots," the authors write.

Two authors disclosed financial ties to the pharmaceutical industry.

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