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Vitiligo Patients Often Exhibit Abnormal Ocular Findings

Patients have significant differences in Schirmer test results, lens, fundus findings

eye

MONDAY, Feb. 29, 2016 (HealthDay News) -- Patients with vitiligo have significant differences in terms of Schirmer test results, lens, and fundus findings, versus controls without systemic disease, according to a study published in the March issue of the International Journal of Dermatology.

Remzi Karadag, M.D., from the Istanbul Medeniyet University, and colleagues examined ocular manifestations in patients with vitiligo. Data were included for 61 patients with vitiligo and 57 controls, without any systemic disease. The authors conducted otorefractometry, keratometry, visual acuity test, intraocular pressure measurement, anterior segment, and fundus examination of the eye with slit lamp, Schirmer test, and perimetry.

The researchers found that the mean Schirmer test results for patients were 16.74 ± 9.11 mm and 17.64 ± 9.41 mm for the right and left eye, respectively, compared with 21.96 ± 12.51 mm and 23.42 ± 12.51 mm for the right and left eye of controls, respectively. Thirty-six eyes from patients and 12 control eyes showed lenticular findings. Some fundus findings were seen in 29 eyes in the vitiligo group and four control eyes. Schirmer test results, lens, and fundus findings differed significantly between the groups (all P < 0.05). There were no significant differences in age, gender, visual acuity, refraction, keratometry, intraocular pressure, perimetry, and corneal findings (all P > 0.05).

"Patients with vitiligo may have more lenticular and retinal findings than normal," the authors write. "They can be more prone to dry eye syndrome as well."

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