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Acquired Melanocytic Nevi Pattern Varies in Whites

Multicenter study finds that skin type predicts prevalence of light brown to dark drown nevi

WEDNESDAY, March 21 (HealthDay News) -- White patients with different skin types show significant differences in the prevalence of acquired melanocytic nevi, according to study findings published in the March issue of the Archives of Dermatology.

Iris Zalaudek, M.D., of the Medical University of Graz in Austria, and colleagues recruited 680 white patients at seven pigmented lesion clinics in Argentina (Buenos Aires), Austria (Graz), Germany (Konstanz), Italy (Naples), New Zealand (Christchurch), Spain (Barcelona) and the United States (Miami) and divided them into four skin-type groups, ranging from I (always burns, never tans) to IV (rarely burns, tans with ease).

After examining dermoscopic images, the researchers found that skin type I was associated with light brown acquired melanocytic nevi with central hypopigmentation and that skin type IV was associated with black nevus characterized by a reticular pattern, central hyperpigmentation and dark brown color. They also found an association between skin types II and III and a multifocal pattern.

"Our results could be the basis for further research into the cellular mechanisms of UV protection, with particular interest in the black nevus," the authors conclude. "In addition, further studies are needed to better clarify the role of UV irradiation on nevogenesis and its influence on dermoscopic nevus patterns."

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