April 2012 Briefing - Dermatology

Here are what the editors at HealthDay consider to be the most important developments in Dermatology for April 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Sunscreen Use May Lead to Vitamin D Deficiency

FRIDAY, April 27 (HealthDay News) -- Using the amount and sun protection factor (SPF) of sunscreen recommended by the World Health Organization (WHO) is associated with little or no vitamin D production, suggesting that regular sunscreen use may lead to vitamin D deficiency, according to research published online April 18 in the British Journal of Dermatology.

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Subtype Best Predictor of Basal Cell Carcinoma Invasion Depth

THURSDAY, April 26 (HealthDay News) -- Basal cell carcinoma (BCC) subtype identified on biopsy and excision specimens is the best predictor of depth of invasion, according to a study published online April 16 in the Journal of the American Academy of Dermatology.

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Study Compares Effectiveness of Psoriasis Treatments

FRIDAY, April 20 (HealthDay News) -- The effectiveness of therapies for psoriasis is variable, and may be lower in real-world settings than in trial settings, according to a study published in the April issue of the Archives of Dermatology.

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Basal Cell Carcinoma on Ear Significantly More Aggressive

WEDNESDAY, April 18 (HealthDay News) -- Basal cell carcinoma (BCC) on the ear is significantly more likely to be aggressive, and occurs more frequently in men, according to a study published in the May issue of the Journal of the American Academy of Dermatology.

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2001 to 2006 Saw Increase in Mohs Surgery for Skin Cancer

TUESDAY, April 17 (HealthDay News) -- For Medicare beneficiaries, the rate of use of Mohs micrographic surgery (MMS) to treat nonmelanoma skin cancer (NMSC) doubled from 2001 through 2006, according to research published in the April issue of the Archives of Dermatology.

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High SPF Sunscreens Assure Protection From Solar Rays

MONDAY, April 16 (HealthDay News) -- An application of water-resistant sunscreen with a sun protection factor (SPF) of 70 or higher adequately protects people against skin cancer and photodamage even when applied irregularly, according to a study published online April 1 in the Journal of the American Academy of Dermatology.

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Small Number of Genes Involved in X-Linked Ichthyosis

THURSDAY, April 12 (HealthDay News) -- Patients with X-linked recessive ichthyosis (XLRI) have altered expression in a small number of genes, and although moisturizer treatment improves dryness, it doesn't affect other biophysical properties or gene expression, according to a study published online April 5 in the British Journal of Dermatology.

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Methotrexate and Azathioprine Equally Efficacious for Eczema

FRIDAY, April 6 (HealthDay News) -- Methotrexate and azathioprine may be equally effective in treating severe atopic eczema in adults, according to a critical appraisal of a study published in the April issue of the British Journal of Dermatology.

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Medical Malpractice Claims Incur Substantial Defense Costs

WEDNESDAY, April 4 (HealthDay News) -- Defense costs for medical malpractice claims vary among specialties and are higher for claims that result in indemnity payments, according to a letter published in the April 5 issue of the New England Journal of Medicine.

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Melanoma Incidence Increasing Among Young Adults

MONDAY, April 2 (HealthDay News) -- From 1970 to 2009, there was an increase in the incidence of melanoma among young adults, particularly females, according to a study published in the April issue of the Mayo Clinic Proceedings.

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Inhibition of Immune Pathway May Trigger Melanoma Growth

MONDAY, April 2 (HealthDay News) -- Melanocyte expression of an immune inhibitory molecule, B7-H1, is associated with the presence of tumor-infiltrating lymphocytes (TILs), according to a study published in the March 28 issue of Science Translational Medicine.

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