June 2011 Briefing - Dermatology

Here are what the editors at HealthDay consider to be the most important developments in Dermatology for June 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Mutations Affect Susceptibility to Fungal Infection

WEDNESDAY, June 29 (HealthDay News) -- In patients with autosomal dominant chronic mucocutaneous candidiasis (CMC), mutations in signal transducer and activator of transcription 1 (STAT1) may be associated with increased susceptibility to fungal infections, according to a study published online June 29 in the New England Journal of Medicine.

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Vitamin D, Calcium Don't Reduce Nonmelanoma Skin Cancer

TUESDAY, June 28 (HealthDay News) -- Low-dose vitamin D and calcium supplementation do not reduce the overall incidence of nonmelanoma skin cancer (NMSC) in postmenopausal women, but may benefit women with a history of NMSC, according to a study published online June 27 in the Journal of Clinical Oncology.

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Cocaine Use Linked to Ear and Trunk Retiform Purpura

MONDAY, June 27 (HealthDay News) -- Use of cocaine may be associated with clinical findings of ear purpura, retiform purpura of the trunk, and neutropenia, according to a study published online June 9 in the Journal of American Academy of Dermatology.

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Limited Formalin Exposure May Impair Disease Diagnosis

THURSDAY, June 23 (HealthDay News) -- Limited exposure to formalin may impair the immunogenicity of some biopsy specimens for select diseases, according to a study published in the July issue of the Journal of the American Academy of Dermatology.

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Topical Tacrolimus May Provide Temporary Relief for CLE

THURSDAY, June 23 (HealthDay News) -- Topical application of tacrolimus 0.1 percent ointment may provide temporary relief for acute, edematous, non-hyperkeratotic lesions in patients with cutaneous lupus erythematosus (CLE), according to a study published in the July issue of the Journal of the American Academy of Dermatology.

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Melanoma Screening Advised for High-Risk Patients

WEDNESDAY, June 22 (HealthDay News) -- Screening for early melanoma detection should be focused on the at-risk population, according to a study published in the June issue of the Archives of Dermatology.

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AbobotulinumtoxinA Beneficial for Lateral Orbital Rhytid

WEDNESDAY, June 22 (HealthDay News) -- Commercially available botulinum neuromodulator, abobotulinumtoxinA, is significantly superior to onabotulinumtoxinA in the treatment of lateral orbital rhytids, according to a study published online June 20 in the Archives of Facial Plastic Surgery.

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Chronic Pruritus Adversely Impacts Quality of Life

WEDNESDAY, June 22 (HealthDay News) -- Chronic pruritus may affect quality of life (QoL) and, after adjusting for confounding variables, is found to have a similar impact to chronic pain, according to a study published online June 16 in the Archives of Dermatology.

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Antirheumatic Drugs Linked to Lower Diabetes Risk

TUESDAY, June 21 (HealthDay News) -- Treatment of rheumatoid arthritis (RA) or psoriasis with biologic disease-modifying antirheumatic drugs (DMARDs), such as tumor necrosis factor (TNF) inhibitors, methotrexate, and hydroxychloroquine, may reduce the risk of newly recorded diabetes mellitus (DM), according to a study published in the June 22/29 issue of the Journal of the American Medical Association.

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Etanercept May Be a Treatment Option for Dermatomyositis

TUESDAY, June 21 (HealthDay News) -- Etanercept appears safe with a steroid sparing effect in the treatment of dermatomyositis, according to a study published online June 17 in the Annals of Neurology.

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Generic Versions of Levofloxacin Approved

MONDAY, June 20 (HealthDay News) -- The first generic versions of levofloxacin, prescribed under the brand name Levaquin, have been approved by the U.S. Food and Drug Administration.

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Unequal Care Access for Children With Public Insurance

THURSDAY, June 16 (HealthDay News) -- Access to outpatient care is restricted for children with public insurance compared to those with private insurance, according to a study published in the June 16 issue of the New England Journal of Medicine.

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Life Expectancy in U.S. Counties Below Many Nations

WEDNESDAY, June 15 (HealthDay News) -- Most counties within the United States fall behind the international frontier with the best life expectancies in the world, according to a study published online June 15 in Population Health Metrics.

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Similar Number for Outpatient, Inpatient Malpractice Claims

TUESDAY, June 14 (HealthDay News) -- The number of paid malpractice claims is similar in both inpatient and outpatient settings, according to a study published in the June 15 issue of the Journal of the American Medical Association.

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FDA Announces Sunscreen Label Changes

TUESDAY, June 14 (HealthDay News) -- The U.S. Food and Drug Administration has announced that sunscreen products that meet modern standards of effectiveness may be labeled with new information to help consumers reduce the risk of skin cancer, prevent sunburn, and lower the risk of early skin aging.

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Adhesive Strips Offer Cosmetic Solution for Cheek Defects

THURSDAY, June 9 (HealthDay News) -- Buried sutures with adhesive strip closure may offer a cosmetically viable alternative to layered closure for repair of excision wounds of skin malignancy in cheeks, according to a study published in the June issue of the Journal of the American Academy of Dermatology.

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Mohs Surgery Effective for Cutaneous Leiomyosarcoma

WEDNESDAY, June 8 (HealthDay News) -- Mohs micrographic surgery (MMS) may effectively treat and prevent tumor recurrence in patients with cutaneous leiomyosarcoma, according to a study published in the June issue of the Journal of the American Academy of Dermatology.

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Parkinson's Disease Linked to Higher Melanoma Occurrence

WEDNESDAY, June 8 (HealthDay News) -- Parkinson's disease (PD) is associated with a moderately higher occurrence of melanoma, according to a review published in the June 7 issue of Neurology.

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Melanoma Vaccine May Enhance Interleukin-2 Efficacy

WEDNESDAY, June 1 (HealthDay News) -- Patients with advanced melanoma who are treated with interleukin-2 and melanoma vaccine may have an improved clinical response and longer survival than those treated with interleukin-2 alone, according to a study published in the June 2 issue of the New England Journal of Medicine.

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