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November 2006 Briefing - Dermatology

Here are what the editors at HealthDay consider to be the most important developments in Dermatology for November 2006. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Surgical Techniques Improve HIV-Associated Facial Wasting

WEDNESDAY, Nov. 29 (HealthDay News) -- HIV-associated facial lipoatrophy can be successfully treated with either lipofilling or submalar silicone implants, according to a study published in the November issue of the Journal of Plastic, Reconstructive & Aesthetic Surgery.

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Complications Studied in Abdominoplasty

WEDNESDAY, Nov. 29 (HealthDay News) -- Abdominoplasty is associated with high rates of early and late complications and the need for revision surgery, according to study findings published in the November issue of the Journal of Plastic, Reconstructive & Aesthetic Surgery.

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Smoking Status Unclear in Plastic Surgery Candidates

WEDNESDAY, Nov. 29 (HealthDay News) -- Patients undergoing elective plastic surgery may often falsely report non-smoking status or underestimate the number of cigarettes they smoke, according to the results of a study published in the November issue of the Journal of Plastic, Reconstructive & Aesthetic Surgery.

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Factors Improve Density of Male Baldness Hair Implants

TUESDAY, Nov. 28 (HealthDay News) -- For men with male pattern baldness, follicular density improves by about 15 percent if the follicular units are embedded with autologous platelet plasma growth factors when implanted, researchers report in the November issue of Plastic and Reconstructive Surgery.

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Gene Mutation Is Main Cause of Harlequin Ichthyosis

TUESDAY, Nov. 28 (HealthDay News) -- Mutations in the ABCA12 gene have been found in additional patients with harlequin ichthyosis, more firmly establishing the gene as the main cause of the disease, according to a report in the November issue of the Journal of Investigative Dermatology. The finding could lead to prenatal or preimplantation genetic tests for carriers of the mutation.

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Atopic Eczema Patients Often Sensitized to Yeast Strain

MONDAY, Nov. 27 (HealthDay News) -- About half of patients with atopic eczema have a sensitivity to the yeast Malassezia sympodialis, according to a report in the November issue of the Journal of Investigative Dermatology.

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Follicular Unit Extraction Studied in Hair Transplants

MONDAY, Nov. 27 (HealthDay News) -- In hair transplant patients, follicular unit extraction (FUE) has some advantages over classical strip harvesting but is limited by a high rate of transection, researchers report in the November issue of Dermatologic Surgery.

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Pigmented Basal Cell Carcinomas Studied

FRIDAY, Nov. 24 (HealthDay News) -- For complete tumor resection, pigmented basal cell carcinomas (PBCC) require a smaller surgical margin than non-pigmented basal cell carcinomas (NPBCC), according to the results of a study published in the November issue of Dermatologic Surgery.

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Silicone Breast Implants Have Low Rupture Rate in Study

THURSDAY, Nov. 23 (HealthDay News) -- The Style 410 silicone breast implants introduced in 1993 are safe with a low rate of rupture, and most women receiving the implants report being satisfied, researchers report in the November issue of Plastic and Reconstructive Surgery.

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Imiquimod Improves Anal Neoplasia in Men with HIV

THURSDAY, Nov. 23 (HealthDay News) -- The local immune response modifier imiquimod appears to be safe and effective for treating anal intraepithelial neoplasia in HIV-positive men, according to the results of an open-label pilot study published in the November issue of the Archives of Dermatology.

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Tumors Not Usually Found in Mastectomy Scars

WEDNESDAY, Nov. 22 (HealthDay News) -- The routine histologic examination of clinically unsuspected mastectomy scars does not help identify any new or metastatic tumors, researchers report in the November issue of Plastic and Reconstructive Surgery.

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Injections Counter HIV-Associated Facial Wasting

WEDNESDAY, Nov. 22 (HealthDay News) -- In patients with HIV-associated facial wasting, or lipoatrophy, treatment with serial injections of poly-L-lactic acid (PLLA) is safe, effective and well-tolerated, according to the results of a study published in the November issue of Dermatologic Surgery.

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Melanoma Thickness Unrelated to Time of Diagnosis

WEDNESDAY, Nov. 22 (HealthDay News) -- The thickness of melanoma is not correlated with the time to first diagnosis by a physician or to the time from diagnosis to invasive disease, according to a report in the November issue of the Archives of Dermatology.

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Psoriasis Plaque Thickness Linked to Disease Traits

WEDNESDAY, Nov. 22 (HealthDay News) -- The thickness of psoriatic plaques may be associated with other psoriasis presentations and may help to shed light on its genetic characteristics, according to a report in the November issue of the Journal of Investigative Dermatology.

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Four Botulism Cases Due to Unlicensed Botulinum Toxin

TUESDAY, Nov. 21 (HealthDay News) -- Four cases of botulism occurred when a suspended clinician used an unlicensed preparation of botulinum toxin A for cosmetic purposes, with some patients receiving doses more than 40 times the estimated lethal dose in humans, according to the Nov. 22/29 issue of Journal of the American Medical Association.

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Long-Term Botox Appears Safe, Effective for Facial Lines

TUESDAY, Nov. 21 (HealthDay News) -- Botulinum toxin type A (Botox, Allergan) appears to be well-tolerated and effective in preventing imprinted facial lines over a 13-year treatment course, according to a study that compared a pair of identical twin sisters, one regularly treated and one minimally treated. The study findings are published in the November/December issue of the Archives of Facial Plastic Surgery.

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Cancer Drug Causes Thin Hair, Depigmentation in Patient

TUESDAY, Nov. 21 (HealthDay News) -- A patient treated with oral doses of the chemotherapeutic tyrosine kinase inhibitor GW786034 unexpectedly developed depigmented and thin hair, according to a case report published in the November issue of the Archives of Dermatology. The authors speculate that topical receptor tyrosine kinase inhibitors may have a hidden potential as a treatment for unwanted body hair.

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Marathon Runners May Have Higher Skin Cancer Risk

TUESDAY, Nov. 21 (HealthDay News) -- Marathon runners are at a higher risk of developing malignant melanoma and non-melanoma skin cancer than the general population because of their longer exposure to the sun, researchers report in the November issue of the Archives of Dermatology.

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Lipid-Producing Gene Marked as Regulator of Hair Growth

WEDNESDAY, Nov. 15 (HealthDay News) -- Researchers have identified the phospholipase gene LIPH as an important regulator of hair growth, according to a report in the Nov. 10 issue of Science. The gene regulates the production of bioactive lipids and may be a new therapeutic target for hair loss.

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Periorificial Dermatitis Strikes Children of All Ages

FRIDAY, Nov. 10 (HealthDay News) -- Periorificial dermatitis affects children and adolescents of all ages and may be associated with topical steroid use, according to the findings of a retrospective chart review published in the November issue of the Journal of the American Academy of Dermatology.

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Cholesterol Embolism Frequently Misdiagnosed

FRIDAY, Nov. 10 (HealthDay News) -- Cholesterol embolism is a frequently misdiagnosed condition, according to a report published in the November issue of the Journal of the American Academy of Dermatology.

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Use of Placebo Controls in Psoriasis Studies Varies

THURSDAY, Nov. 9 (HealthDay News) -- There is wide variation in the use of placebo controls in psoriasis studies, depending on location and funding source, according to a report published in the November issue of the Journal of the American Academy of Dermatology.

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Hot Air Cures Head Lice Infestation

MONDAY, Nov. 6 (HealthDay News) -- Hot air seems to be a safe and effective treatment for head lice, and one method of heat application was 100 percent effective at curing lice infestation after a single 30-minute treatment, according to a report in the November issue of Pediatrics.

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