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Metabolic Syndrome Prevalence High in Psoriasis Patients

40 percent of those with psoriasis have the condition

TUESDAY, Dec. 28 (HealthDay News) -- The metabolic syndrome occurs substantially more frequently in people with psoriasis than in the general population, according to research published online Dec. 20 in the Archives of Dermatology.

Thorvardur Jon Love, M.D., of Brigham and Women's Hospital and Harvard Medical School in Boston, and colleagues reviewed data on 6,549 participants of the National Health and Nutrition Examination Survey, 2003 to 2006, to determine the prevalence of the metabolic syndrome among people with psoriasis and associations between the two conditions.

The researchers found that the metabolic syndrome occurred among 23 percent of controls and 40 percent of subjects with psoriasis. According to projections of 2008 U.S. census data, 2.7 million people with psoriasis were estimated to have the metabolic syndrome. The univariate and multivariate odds ratios of those who had psoriasis and the metabolic syndrome were 2.16 and 1.96, respectively. Dominant features of the metabolic syndrome in those with psoriasis included abdominal obesity, hypertriglyceridemia, and low levels of high-density lipoprotein cholesterol.

"The prevalence of the metabolic syndrome is high among individuals with psoriasis. Given the serious complications associated with the metabolic syndrome, this frequent comorbidity should be recognized and taken into account in the long-term treatment of individuals with psoriasis," the authors write.

One author disclosed several financial relationships with pharmaceutical companies.

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