Periorificial Dermatitis Strikes Children of All Ages

New research elucidates manifestations, treatment outcomes of common mouth rash

FRIDAY, Nov. 10 (HealthDay News) -- Periorificial dermatitis affects children and adolescents of all ages and may be associated with topical steroid use, according to the findings of a retrospective chart review published in the November issue of the Journal of the American Academy of Dermatology.

Victoria Nguyen, M.D., and Lawrence F. Eichenfield, M.D., of the University of California San Diego School of Medicine, evaluated the clinical manifestations and treatment outcomes among 79 children and adolescents with periorificial dermatitis.

Patients were aged 6 months to 18 years, and their average rash duration at presentation was eight months. In the study, 72 percent of patients had a history of steroid use. Seventy percent of study patients had perioral involvement, 43 percent had perinasal involvement, one-quarter had periocular involvement and 1 percent reported a perivulvar rash. The use of topical metronidazole tended to clear the rash in about seven weeks.

"Perioral dermatitis…may be responsive to topical metronidazole in children and adolescents and is more appropriately termed periorificial dermatitis," the researchers conclude.

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