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Factors in Diabetics' Artery Calcification Examined

Prior calcification, poor glycemic control increase risk for coronary arteries

TUESDAY, Nov. 27 (HealthDay News) -- Type 2 diabetic patients have a higher risk of coronary artery calcification if they have prior calcification, poor glycemic control or take statins, researchers report in the Dec. 4 issue of the Journal of the American College of Cardiology.

Dhakshinamurthy Vijay Anand, from Wellington Hospital in London, United Kingdom, and colleagues examined factors affecting the progression of coronary artery calcification in 398 patients with type 2 diabetes without prior coronary disease or symptoms.

The researchers found that 53 percent of patients had coronary artery calcification at baseline, 29.6 percent had progression, and 0.8 percent had regression. Independent predictors of coronary artery calcification progression were baseline calcification (odds ratio 6.38 for coronary artery calcification greater than 400), glycated hemoglobin greater than 7 (OR, 1.95) and statin use (OR, 2.27).

"Baseline coronary artery calcification severity and suboptimal glycemic control are strong risk factors for coronary artery calcification progression in type 2 diabetic subjects," Anand and colleagues conclude.

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