Type IType I DiabetesHeart / Stroke-RelatedCoronary-Artery Disease Heart / Stroke-RelatedCardiologyDiabetes & EndocrinologyFamily PracticeNursingInternal MedicineCardiovascular DiseasesCoronary-Artery DiseaseDiabetesType 1 Diabetes
HealthDay operates under the strictest editorial standards. Our syndicated news content is completely independent of any financial interests, is based solely on industry-respected sources and the latest scientific research, and is carefully fact-checked by a team of industry experts to ensure accuracy.
- All articles are edited and checked for factual accuracy by our Editorial Team prior to being published.
- Unless otherwise noted, all articles focusing on new research are based on studies published in peer-reviewed journals or issued from independent and respected medical associations, academic groups and governmental organizations.
- Each article includes a link or reference to the original source.
- Any known potential conflicts of interest associated with a study or source are made clear to the reader.
Please see our Editorial and Fact-Checking Policy for more detail.Editorial and Fact-Checking Policy
HealthDay Editorial Commitment
HeathDay is committed to maintaining the highest possible levels of impartial editorial standards in the content that we present on our website. All of our articles are chosen independent of any financial interests. Editors and writers make all efforts to clarify any financial ties behind the studies on which we report.
TUESDAY, Aug. 7 (HealthDay News) -- Skin intrinsic fluorescence (SIF) is significantly associated with coronary artery disease (CAD) in middle-aged adults with a long duration of type 1 diabetes, according to a study published online July 30 in Diabetes Care.
Baqiyyah N. Conway, Ph.D., of Vanderbilt University in Nashville, Tenn., and colleagues conducted a study involving a total of 172 middle-aged adults with type 1 diabetes (mean disease duration, 36 years) to evaluate the relationship between SIF and CAD and whether this relationship was independent of renal disease.
The researchers found that 30 of the participants had CAD, and that SIF levels were significantly higher in those participants with CAD. SIF correlated strongly with CAD (odds ratio [OR], 3.5). The correlation persisted, after adjustment for age, diabetes duration, and cumulative glycemic exposure (OR, 2.4), and was stronger for men (OR, 5.6) than for women (OR, 1.4; 95 percent confidence interval [CI], 0.61 to 3.3). With inclusion of nephropathy in the model, the OR for SIF declined to 1.7 (95 percent CI, 0.89 to 3.4).
"In conclusion, we have demonstrated a strong association between SIF and CAD in middle-aged individuals with type 1 diabetes," the authors write. "SIF partially reflects the influence of skin advanced glycation end products, skin markers of oxidative stress and cell metabolism, subject age, diabetes duration, long-term glycemic control, and renal disease, which are associated with increased CAD risk."
Several authors are employees of or disclosed financial ties to Vera Light Inc., which funded the study and manufactures the SCOUT DS used to determine SIF.
This story may be outdated. We suggest some alternatives.
The content contained in this article is over two years old. As such our recommendation is that you reference the articles below for the latest updates on this topic. This article has been left on our site as a matter of historic record. Please contact us at firstname.lastname@example.org with any questions.
Updated on June 04, 2022
Read this Next
Other Trending Articles