THURSDAY, Aug. 31 (HealthDay News) -- Type 2 diabetics who take sulfonylurea agents and chromium picolinate supplements gain significantly less weight, body fat and abdominal mass than those taking a placebo, researchers report in the August issue of Diabetes Care.
Julie Martin, M.S., R.D., of the University of Vermont in Burlington, and colleagues treated 37 type 2 diabetics with 5 milligrams daily of a sulfonylurea and placebo for three months. They followed this with six months of the same regimen for 12 patients, versus sulfonylurea plus 1,000 μg chromium picolinate supplementation for 17 others.
The researchers found that patients taking sulfonylurea and placebo gained 2.2 kilograms of body weight, versus 0.9 kilograms for those on sulfonylurea and chromium picolinate. Patients taking sulfonylurea and placebo also gained 1.17 percent body fat and 32.5 square centimeters total abdominal fat, while the chromium picolinate group gained 0.12 percent body fat and 12.2 square centimeters abdominal fat.
"This study demonstrates that chromium picolinate supplementation in subjects with type 2 diabetes who are taking sulfonylurea agents significantly improves insulin sensitivity and glucose control," the authors write. "Chromium picolinate supplementation significantly attenuated body weight gain and visceral fat accumulation."
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