Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for January 2013. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Adiposity, Hyperglycemia Tied to Cognitive Performance
THURSDAY, Jan. 31 (HealthDay News) -- Among healthy middle-aged adults, adiposity and hyperglycemia correlate with poor cognitive performance, according to a study published online Dec. 28 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Ranibizumab No Better Than Saline for Vitreous Hemorrhage
THURSDAY, Jan. 31 (HealthDay News) -- For patients with vitreous hemorrhage from proliferative diabetic retinopathy (PDR), the probability of vitrectomy within 16 weeks after intravitreal injections of ranibizumab or saline is lower than expected, with little difference seen between the two treatments, according to a study published online Jan. 31 in JAMA Ophthalmology.
Abstract
Full Text (subscription or payment may be required)
Effect of Obesity Gene Variant Influenced by Age
THURSDAY, Jan. 31 (HealthDay News) -- A genetic variant associated with obesity risk (FTO) has a greater effect on body mass index (BMI) in young adults than older adults, according to a study published online Jan. 8 in Diabetes.
Abstract
Full Text (subscription or payment may be required)
Common Obesity Beliefs Often Unsupported by Science
WEDNESDAY, Jan. 30 (HealthDay News) -- Many commonly held beliefs about obesity and weight loss are not supported by scientific evidence, according to a study published in the Jan. 31 issue of the New England Journal of Medicine.
Full Text (subscription or payment may be required)
Bile Acid Sequestrant Reduces Glucose Concentration in T2DM
WEDNESDAY, Jan. 30 (HealthDay News) -- For patients with type 2 diabetes taking metformin monotherapy, the bile acid sequestrant colesevelam reduces fasting and postprandial glucose concentrations without any effects on insulin concentration, secretion, or action, according to research published online Dec. 18 in Diabetes.
Abstract
Full Text (subscription or payment may be required)
In STEMI, Diabetes Linked to Worse Long-Term Outcomes
TUESDAY, Jan. 29 (HealthDay News) -- In patients undergoing primary angioplasty for ST-segment elevation myocardial infarction (STEMI), diabetes is associated with worse long-term outcomes, including mortality, reinfarction, stent thrombosis, and target vessel revascularization (TVR), according to research published online Dec. 28 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
T1DM Insulin Intensification Patterns, Outcomes Studied
TUESDAY, Jan. 29 (HealthDay News) -- About half of youths with type 1 diabetes shift to a more intensive insulin regimen over time, which is associated with better glycemic control, according to research published in the January issue of Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Physicians Commonly Report Unsafe Hospital Workloads
TUESDAY, Jan. 29 (HealthDay News) -- Physicians say they often face unsafe hospital workloads, according to a study published online Jan. 28 in JAMA Internal Medicine.
Full Text (subscription or payment may be required)
Brain Scans Show Doctors Empathize With Patients
TUESDAY, Jan. 29 (HealthDay News) -- Physicians who empathize with a patient in pain and feel relief when the patient receives effective treatment show activity in brain regions associated with pain relief and reward, according to a study published online Jan. 29 in Molecular Psychiatry.
Abstract
Full Text (subscription or payment may be required)
Less CVD Hospitalization When SBP, LDL-C Controlled in T2DM
MONDAY, Jan. 28 (HealthDay News) -- Patients with type 2 diabetes with controlled systolic blood pressure (SBP) or low-density lipoprotein cholesterol (LDL-C) have significantly lower rates of hospitalization for cardiovascular disease (CVD), especially when both risk factors are controlled, according to research published online Jan. 28 in the Journal of General Internal Medicine.
Abstract
Full Text (subscription or payment may be required)
FDA: Three New Treatments Approved for Type 2 Diabetes
MONDAY, Jan. 28 (HealthDay News) -- Three new products have been approved by the U.S. Food and Drug Administration to improve blood sugar control in adults with type 2 diabetes, for use as monotherapy or in combination with other therapies and together with diet and exercise.
More Information
AAP Releases Guidelines for Pediatric Type 2 Diabetes
MONDAY, Jan. 28 (HealthDay News) -- New guidelines recommend lifestyle modifications together with medications for children and adolescents diagnosed with type 2 diabetes mellitus (T2DM); these clinical practice guidelines from the American Academy of Pediatrics (AAP) have been published online Jan. 28 in Pediatrics.
Abstract
Full Text
Sclerostin Linked to Vascular Disease in Type 2 Diabetes
MONDAY, Jan. 28 (HealthDay News) -- Circulating levels of the Wnt/β-catenin signaling inhibitor sclerostin are higher in patients with type 2 diabetes who also have atherosclerotic disease, according to a study published online Jan. 3 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Weight Counseling Declining Among Primary Care Doctors
MONDAY, Jan. 28 (HealthDay News) -- From 1995-1996 to 2007-2008, the rate of weight counseling provided by primary care physicians (PCPs) decreased significantly, even for those patients with obesity and weight-related comorbidities such as diabetes and hypertension, according to research published in the February issue of Medical Care.
Abstract
Full Text (subscription or payment may be required)
Performance Differences Seen in Continuous Glucose Monitors
FRIDAY, Jan. 25 (HealthDay News) -- Continuous glucose monitoring (CGM) devices vary in performance characteristics, according to a comparative effectiveness study published online Dec. 28 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
ACPE Survey Finds Skepticism Relating to Online Doc Ratings
THURSDAY, Jan. 24 (HealthDay News) -- Physicians are skeptical of online ratings, and believe that few patients use them, according to a survey published by the American College of Physician Executives (ACPE).
More Information
Retinopathy Severity Linked to Cardiovascular Outcome
THURSDAY, Jan. 24 (HealthDay News) -- For individuals with type 2 diabetes, incident cardiovascular outcomes are determined not only by the severity of diabetic retinopathy but also by its progression, according to research published online Dec. 13 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Physician Education Ups Communication for New Meds
THURSDAY, Jan. 24 (HealthDay News) -- A physician-targeted education session improves physician communication about newly-prescribed medications, according to a study published in the January/February issue of the Annals of Family Medicine.
Abstract
Full Text
Cancer Prevalence Higher With Long Duration of Diabetes
THURSDAY, Jan. 24 (HealthDay News) -- Patients diagnosed with type 2 diabetes have a greater prevalence of cancer with longer diabetes duration and with insulin use, according to a study published online Jan. 8 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Large Teaching Hospitals Face More Readmission Penalties
WEDNESDAY, Jan. 23 (HealthDay News) -- Large hospitals, teaching hospitals, and safety-net hospitals (SNHs) are more likely than other hospitals to be penalized under the Centers for Medicare & Medicaid Services' Hospital Readmissions Reduction Program (HRRP), according to a research letter published in the Jan. 23/30 issue of the Journal of the American Medical Association.
Full Text (subscription or payment may be required)
Fatty Liver May Directly Mediate CAD in Metabolic Syndrome
WEDNESDAY, Jan. 23 (HealthDay News) -- Men and women with fatty liver are more likely to have metabolic syndrome (MetS) with type 2 diabetes, and women with fatty liver are more likely to have MetS with subclinical atherosclerosis, according to research published online Dec. 18 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Care Transition Initiative Decreases Rehospitalizations
WEDNESDAY, Jan. 23 (HealthDay News) -- Communities instituting quality improvement initiatives for care transitions see significant declines in the rate of 30-day rehospitalizations and hospitalizations, according to a study published in the Jan. 23/30 issue of the Journal of the American Medical Association.
Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Gestational Diabetes Ups Costs of Maternity Care by One-Third
MONDAY, Jan. 21 (HealthDay News) -- Women with gestational diabetes mellitus (GDM) are significantly more likely to receive an emergency cesarean section, have their infant admitted to a neonatal care unit, and incur significantly higher maternity care costs, compared to women without GDM, according to research published online Dec. 28 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Calorie-Restricted Weight Loss Restores Ghrelin Sensitivity
MONDAY, Jan. 21 (HealthDay News) -- In a mouse model, calorie-restricted weight loss reverses the high-fat diet-induced ghrelin resistance that may contribute to rebound weight gain, according to research published online Jan. 10 in Endocrinology.
Abstract
Full Text (subscription or payment may be required)
Accelerated Cognitive Decline Seen With T2DM in Middle Age
MONDAY, Jan. 21 (HealthDay News) -- Middle-aged patients with type 2 diabetes show accelerated cognitive decline in information processing speed and executive function, according to a study published online Dec. 28 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Coronary Artery Calcium Predicts Cardiovascular Death in T2DM
FRIDAY, Jan. 18 (HealthDay News) -- In addition to traditional cardiovascular disease risk factors, in patients with type 2 diabetes, coronary artery calcium (CAC) predicts the risk of cardiovascular death, according to a study published online Dec. 10 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Physical Activity Requirement in <40 Percent of College Programs
FRIDAY, Jan. 18 (HealthDay News) -- Compared with historic levels, as of 2010, less than 40 percent of four-year universities and colleges in the United States have a physical education requirement for graduation with a baccalaureate degree, according to research published in the December issue of Research Quarterly for Exercise and Sport.
Abstract
Full Text (subscription or payment may be required)
Efforts Failed to Up Primary Care, Rural Resident Training
FRIDAY, Jan. 18 (HealthDay News) -- The 2005 redistribution of graduate medical education (GME) funds did little to train more residents in primary care and in rural areas, according to a study published in the January issue of Health Affairs.
Abstract
Full Text (subscription or payment may be required)
Fasting Plasma Glucose Beats HbA1c for Diabetes Screening
THURSDAY, Jan. 17 (HealthDay News) -- For patients without diabetes undergoing coronary angiography (CAG), fasting plasma glucose (FPG) performs better in diabetes screening than glycated hemoglobin (HbA1c), according to a study published online Dec. 13 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Family Docs Are Early Adopters of Electronic Health Records
WEDNESDAY, Jan. 16 (HealthDay News) -- Family practice physicians are adopting electronic health record (EHR) systems at a fast pace, with 68 percent using an EHR system by 2011, and 80 percent expected to be users by 2013, according to research published in the January/February issue of the Annals of Family Medicine.
Abstract
Full Text
Even Brief Interruptions Dramatically Increase Errors
WEDNESDAY, Jan. 16 (HealthDay News) -- Even momentary interruptions of two to four seconds can significantly affect a person's ability to accurately complete a task requiring considerable thought, according to research published online Jan. 7 in the Journal of Experimental Psychology: General.
Abstract
Full Text (subscription or payment may be required)
Education, Wealth Levels Impact Mortality in Diabetes Patients
WEDNESDAY, Jan. 16 (HealthDay News) -- Socioeconomic status, as measured by education and financial wealth, is a strong independent predictor of mortality risk among adult diabetes patients, according to a study published in the January issue of Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Certain Online Behaviors of Docs Warrant Investigation
MONDAY, Jan. 14 (HealthDay News) -- There is high consensus among state medical boards regarding the likelihood of probable investigations for certain online behaviors, according to a study published in the Jan. 15 issue of the Annals of Internal Medicine.
Full Text (subscription or payment may be required)
Top Five Issues for Docs and Patients Identified for 2013
MONDAY, Jan. 14 (HealthDay News) -- The top five issues that will impact physicians and patients in 2013 have been identified, according to a report published Dec. 10 by The Physicians Foundation.
More Information
Novel Racial/Ethnic Differences Found in Diabetic Kidney Disease
MONDAY, Jan. 14 (HealthDay News) -- Rates of proteinuric and nonproteinuric diabetic kidney disease (DKD) vary significantly across racial/ethnic groups, according to a study published online Dec. 13 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Insulin LY2605541 Tops Glargine for Glycemic Control in T1DM
FRIDAY, Jan. 11 (HealthDay News) -- For patients with type 1 diabetes, the novel, long-acting basal insulin LY2605541 yields greater improvement in glycemic control compared with insulin glargine, according to a study published online Nov. 27 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
National U.S. Health Care Spending Relatively Stable
FRIDAY, Jan. 11 (HealthDay News) -- The growth in national U.S. health care spending was relatively stable in 2011, but growth in personal health care spending accelerated, according to a study published in the January issue of Health Affairs.
Abstract
Full Text (subscription or payment may be required)
High Unawareness of Distal Sensorimotor Polyneuropathy
THURSDAY, Jan. 10 (HealthDay News) -- A high percentage of older adults with diabetes and prediabetes are unaware of having clinical distal sensorimotor polyneuropathy (DSPN), according to a study published online Dec. 28 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
SPIRIT 2013 Clinical Trial Protocol Guidelines Issued
THURSDAY, Jan. 10 (HealthDay News) -- A panel of experts, including trial investigators, trial coordinators, and representatives from ethics and regulatory agencies, has developed the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 guidelines for the minimum content of a clinical trial, according to a statement published online Jan. 8 in the Annals of Internal Medicine.
Abstract
Full Text
Americans Sicker, Die Younger Than Other Developed Nations
WEDNESDAY, Jan. 9 (HealthDay News) -- Americans have worse health than their peers in high-income countries, according to a report published Jan. 9 by the National Research Council and Institute of Medicine.
More Information
Multiple Stressors Contribute to Readmission Within 30 Days
WEDNESDAY, Jan. 9 (HealthDay News) -- Nearly one-fifth of Medicare patients discharged from the hospital are readmitted within 30 days, which seems to arise from a combination of factors contributing to patient vulnerability, according to research published in the Jan. 9 issue of the New England Journal of Medicine.
Full Text
Vitamin D Does Not Improve Knee OA Progression, Symptoms
WEDNESDAY, Jan. 9 (HealthDay News) -- For adults with symptomatic knee osteoarthritis (OA), vitamin D supplementation for two years does not reduce knee pain or cartilage volume loss compared to placebo, according to a study published in the Jan. 9 issue of the Journal of the American Medical Association.
Abstract
Full Text
Health Care Use Dropped Among All During Recession
TUESDAY, Jan. 8 (HealthDay News) -- Health care use declined significantly among all races and ethnicities during the recession from 2007 to 2009, with the only ethnic disparity being fewer physician visits by Hispanics compared with whites, according to a study published online Jan. 7 in JAMA Internal Medicine.
Full Text (subscription or payment may be required)
Fetuin-A Levels Linked to Cardiovascular Disease Risk
TUESDAY, Jan. 8 (HealthDay News) -- In elderly individuals without type 2 diabetes, high levels of fetuin-A, a protein that inhibits arterial calcification and insulin action, is associated with a lower risk of cardiovascular disease, according to a study published online Dec. 18 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Maternal Vitamin D Levels Tied to Growth in Term Infants
TUESDAY, Jan. 8 (HealthDay News) -- Higher first-trimester maternal 25-hydroxyvitamin D (25[OH]D) levels are significantly linked to markers of growth in term infants, according to a study published in the Jan. 1 issue of the Journal of Clinical Endocrinology & Metabolism.
Abstract
Full Text (subscription or payment may be required)
Microaneurysm Turnover IDs Macular Edema Development
TUESDAY, Jan. 8 (HealthDay News) -- Microaneurysm (MA) turnover independently predicts the development of clinically significant macular edema (CSME) in patients with non-proliferative diabetic retinopathy (NPDR), according to a study published online Nov. 30 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Shared Savings May Promote Care Coordination Entity Use
MONDAY, Jan. 7 (HealthDay News) -- Use of shared savings could encourage individuals who are dually eligible for Medicare and Medicaid to enroll in state-designed care coordination entities (CCEs), according to a perspective piece published online Jan. 2 in the New England Journal of Medicine.
Full Text
Metformin Cuts Cardio Events in High-Risk Type 2 Diabetes
MONDAY, Jan. 7 (HealthDay News) -- Metformin therapy significantly reduces cardiovascular events in high-risk patients with type 2 diabetes compared to treatment with glipizide, according to a study published online Dec. 10 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Patient-Doctor Communication Affects Medication Adherence
FRIDAY, Jan. 4 (HealthDay News) -- Poor communication between patients and health care providers is linked to lower cardiometabolic medication adherence, according to a study published online Dec. 31 in JAMA Internal Medicine.
Abstract
Full Text (subscription or payment may be required)
Association Between Health Care Cost, Quality Inconsistent
THURSDAY, Jan. 3 (HealthDay News) -- The direction of the association between health care cost and quality is unclear, with inconsistent evidence indicating positive, negative, mixed, and indeterminate associations, according to a review published in the Jan. 1 issue of the Annals of Internal Medicine.
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Fracture Risk Down With Adherence to Bisphosphonates
THURSDAY, Jan. 3 (HealthDay News) -- For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate treatment is over 50 percent, according to two studies published in the December issue of Arthritis Care & Research.
Abstract - Curtis
Full Text (subscription or payment may be required)
Abstract - Richards
Full Text (subscription or payment may be required)
TPN-Linked Hyperglycemia Ups Death for Non-Critically Ill
THURSDAY, Jan. 3 (HealthDay News) -- Non-critically ill hospitalized patients who develop hyperglycemia after total parenteral nutrition (TPN) are more than five times more likely to die in the hospital, according to research published online Dec. 6 in Diabetes Care.
Abstract
Full Text (subscription or payment may be required)
Telmisartan Reverses Insulin Resistance in Mice
THURSDAY, Jan. 3 (HealthDay News) -- Treating mice fed a high-fat diet with telmisartan reverses insulin resistance and glucose intolerance, but only when the peroxisome proliferator-activated receptor-δ (PPAR-δ) gene is present, according to a study published online Dec. 13 in Diabetes.
Abstract
Full Text (subscription or payment may be required)
Review: All-Cause Mortality Down for Mildly Overweight
WEDNESDAY, Jan. 2 (HealthDay News) -- Obesity (all grades combined) and grades 2 and 3 obesity, based on standard body mass index (BMI) categories, correlate with increased risk of all-cause mortality, while overweight is associated with decreased risk compared with normal weight, according to a review published in the Jan. 2 issue of the Journal of the American Medical Association.
Abstract
Full Text
Editorial (subscription or payment may be required)
Glucose, Fructose Affect Cerebral Blood Flow Differently
WEDNESDAY, Jan. 2 (HealthDay News) -- Ingestion of fructose is associated with a distinct pattern of regional cerebral blood flow compared with glucose, which has implications for appetite regulation, according to a study published in the Jan. 1 issue of the Journal of the American Medical Association.
Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
House Joins Senate to Avert Medicare Cuts
WEDNESDAY, Jan. 2 (HealthDay News) -- The House of Representatives settled on an 11th-hour agreement late Tuesday night that has averted the widespread tax increases and spending cuts that would have gone into effect January 1. This agreement occurred 21 hours after the U.S. Senate did its part to steer the country clear of the "fiscal cliff."
More Information
Travel-Based Interventions May Be As Effective As Diet on BMI
TUESDAY, Jan. 1 (HealthDay News) -- Cutting car travel can be as effective as reducing calories in lowering body mass index (BMI), according to research published online Dec. 5 in Preventive Medicine.
Abstract
Full Text (subscription or payment may be required)
