June 2015 Briefing - Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for June 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Three Issues to Consider Before Selecting EHR

TUESDAY, June 30, 2015 (HealthDay News) -- Work flow, features and functionality, and technical infrastructure should all be considered in advance of selecting an electronic heath record (EHR) system, according to an article published in Medical Economics.

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Patients Want Online Access to Physicians, Health Records

TUESDAY, June 30, 2015 (HealthDay News) -- Internet-savvy Americans would like to add their doctors to their group of Facebook friends or e-mail contacts, according to a study published online June 24 in the Journal of General Internal Medicine.

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Hormone May Be Key to Sugar, Diet Sweetener Response

TUESDAY, June 30, 2015 (HealthDay News) -- Artificial sweeteners don't contain the calories or energy that evolution has trained the brain to expect from sweet-tasting foods, thereby failing to satisfy hunger, and a specific hormone may be the key to the process, according to an experimental study published online June 11 in Neuron.

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AMA Discusses Pre-Retirement Evaluation for Aging Doctors

MONDAY, June 29, 2015 (HealthDay News) -- Issues relating to physician retirement and evaluation of aging physicians before retirement are discussed in a Council on Medical Education report published by the American Medical Association (AMA).

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Low-Calorie Diet May Improve Heart Rate Variability in Diabetes

MONDAY, June 29, 2015 (HealthDay News) -- A low-calorie diet may improve heart rate variability (HRV) in obese patients with type 2 diabetes, according to a study published online June 12 in Diabetes Care.

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Maternal Hyperglycemia Not Linked to Obesity in Offspring

MONDAY, June 29, 2015 (HealthDay News) -- Maternal hyperglycemia seems not to be a risk factor for obesity in offspring aged 5 to 7 years after adjustment for maternal body mass index (BMI), according to a study published online June 19 in Diabetes Care.

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U.S. Dietary Guidelines Will No Longer Focus on Fat

MONDAY, June 29, 2015 (HealthDay News) -- Nutrition experts are supporting a federal decision to drop recommended restrictions on total fat consumption in the forthcoming 2015 Dietary Guidelines for Americans.

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As U.S. Smoking Rate Drops, Smokers More Likely to Quit

MONDAY, June 29, 2015 (HealthDay News) -- As the number of smokers in the United States drops, those who still light up are smoking less and more likely to try quitting, according to a study published online June 24 in Tobacco Control.

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Alteration in Intestinal Microbiota Tied to T1DM Susceptibility

FRIDAY, June 26, 2015 (HealthDay News) -- Individuals with islet autoimmunity have alterations in intestinal microbiota, according to a study published online June 19 in Diabetes.

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SCOTUS Upholds Subsidies for Affordable Care Act

FRIDAY, June 26, 2015 (HealthDay News) -- The U.S. Supreme Court upheld on Thursday the legality of tax subsidies for millions of Americans who signed up for health insurance under the Affordable Care Act.

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Steroid Avoidance May Not Help Reduce Posttransplant Diabetes

FRIDAY, June 25, 2015 (HealthDay News) -- For kidney transplant recipients, steroid avoidance has limited impact for reducing new-onset diabetes after transplantation (NODAT), according to a study published in the July issue of the American Journal of Transplantation.

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High-Sensitivity CRP Linked to Incident Type 2 Diabetes

FRIDAY, June 26, 2015 (HealthDay News) -- High-sensitivity C-reactive protein (hs-CRP) is associated with diabetes in African-Americans, according to a study published online June 11 in Diabetes Care.

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'Smart Insulin Patch' Holds Promise for T1DM

THURSDAY, June 25, 2015 (HealthDay News) -- A microneedle-array patch ("smart insulin patch") containing glucose-responsive vesicles (GRVs), which are loaded with insulin and sensitive to hypoxia, can regulate blood glucose in a mouse model of type 1 diabetes. The findings were published online June 22 in the Proceedings of the National Academy of Sciences.

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Providers' Electronic Notes Tied to Better Glycemic Control

THURSDAY, June 25, 2015 (HealthDay News) -- A higher quantity of electronically documented notes on lifestyle counseling of patients with diabetes is tied to improved glycemic control, according to a study published online June 12 in Diabetes Care.

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Proof-of-Concept Study to Assess Impact of Glycemic Variability

WEDNESDAY, June 24, 2015 (HealthDay News) -- A proof-of-concept study will be able to examine the contribution of glycemic variability to outcomes of type 2 diabetes, according to a report published online June 11 in Diabetes Care.

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Gut Microbe Could Aid Weight Loss, Improve Metabolic Health

WEDNESDAY, June 24, 2015 (HealthDay News) -- The gut microbe Akkermansia muciniphila is associated with healthier metabolic status, according to research published online June 22 in Gut.

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Timing of Carb Intake During Meal Affects Glucose Levels

WEDNESDAY, June 24, 2015 (HealthDay News) -- The order in which individuals with type 2 diabetes eat their food can affect their blood glucose levels, according to a small study published in the July issue of Diabetes Care.

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In Teens, Sedentary Behavior Independently Tied to Adiposity

WEDNESDAY, June 24, 2015 (HealthDay News) -- For adolescents, sedentary behavior is associated with markers of adiposity, independent of dietary intake, according to a systematic review published online June 22 in Obesity Reviews.

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VA/DoD Release Guidelines for Dyslipidemia Management

TUESDAY, June 23, 2015 (HealthDay News) -- A joint clinical practice guideline for the management of dyslipidemia for cardiovascular disease risk reduction in adults has been summarized and published online June 22 in the Annals of Internal Medicine.

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Researchers Report U.S. Obesity Epidemic Getting Worse

MONDAY, June 22, 2015 (HealthDay News) -- About 35 percent of men and 37 percent of women are obese, while 40 percent of men and 30 percent of women are overweight, according to a research letter published online June 22 in JAMA Internal Medicine.

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Islet Transplantation Safe, Efficient in Five-Year Follow-Up

MONDAY, June 22, 2015 (HealthDay News) -- Islet transplantation seems safe and efficient for restoring glycemic control in type 1 diabetes, according to research published online June 11 in Diabetes Care.

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Medical Identity Theft Incidents Increasing

MONDAY, June 22, 2015 (HealthDay News) -- Medical identity theft is on the rise, costly to consumers, and challenging to resolve, according to the fifth annual report published by the Ponemon Institute.

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Subclinical Hypothyroidism Ups DM Risk Only With Statin Use

MONDAY, June 22, 2015 (HealthDay News) -- Hypothyroidism is associated with increased risk of diabetes mellitus (DM); however, subclinical hypothyroidism appears to increase this risk only with statin use, according to research published online June 12 in Diabetes Care.

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Caution in Social Media Age: Self-Promotion Can Backfire

FRIDAY, June 19, 2015 (HealthDay News) -- In a series of experiments, researchers found that people who self-promote often offend others. The study was published in the June issue of Psychological Science.

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Exercise-Induced Capillary Density Ups Insulin Sensitivity

FRIDAY, June 19, 2015 (HealthDay News) -- Exercise training is associated with an increase in skeletal muscle capillary density (CD), which contributes to improvements in glucose metabolism, according to a study published online June 11 in Diabetes.

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Hundreds Arrested Nationwide for Medicare/Medicaid Fraud

FRIDAY, June 19, 2015 (HealthDay News) -- Hundreds of people have been charged after health care fraud sweeps were made across the United States, the federal government said Thursday.

Health Highlights: June 19, 2015

FDA Cracks Down on Online Sale of Illegal Medical Products

FRIDAY, June 19, 2015 (HealthDay News) -- The U.S. Food and Drug Administration, along with international partners, moved this week against more than 1,050 websites that sell potentially dangerous counterfeit medicines and medical devices, the agency said Thursday.

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Virtual Credit Card Fees Amount to 3 to 5 Percent of Payments

THURSDAY, June 18, 2015 (HealthDay News) -- Payment with virtual credit cards (VCCs) is associated with considerable fees, although physicians are often unaware of these charges, according to the American Medical Association (AMA).

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Increased Sleep Duration Linked to Increased T2DM Risk

THURSDAY, June 18, 2015 (HealthDay News) -- Increased sleep duration is associated with increased risk of incident type 2 diabetes, according to a study published online June 11 in Diabetes Care.

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Increased Infection-Linked Mortality in DM Greater for T1DM

WEDNESDAY, June 17, 2015 (HealthDay News) -- Patients with diabetes have increased risk of mortality from various infections, and the increased risk appears to be greater for type 1 than type 2 diabetes, according to a study published online June 12 in Diabetes Care.

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Maternal Stress-Linked Changes in Vaginal Microbiota Explored

WEDNESDAY, June 17, 2015 (HealthDay News) -- Maternal stress-induced changes in the vaginal microbiota impact vaginal immunity and metabolic processes, according to an experimental study published online June 16 in Endocrinology.

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Direct Messaging Not Yet Widely Adopted by Physicians

TUESDAY, June 16, 2015 (HealthDay News) -- Direct secure messaging (Direct), which is a standardized protocol for exchanging clinical messages and attachments, has not been widely adopted by physicians, despite its potential for improving care coordination, according to an article published in Medical Economics.

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FDA: Food Manufacturers Have 3 Years to Remove Trans Fats

TUESDAY, June 16, 2015 (HealthDay News) -- In a move that it says is designed to protect the heart health of Americans, the U.S. Food and Drug Administration said Tuesday that food manufacturers have three years to remove artificial trans fats from the nation's food supply.

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Prenatal DDT Exposure Tied to Higher Breast Cancer Risk

TUESDAY, June 16, 2015 (HealthDay News) -- Although the pesticide dichlorodiphenyltrichloroethane (DDT) was banned in the United States in 1972, women exposed to the chemical in utero may be more likely to develop breast cancer than women who had less exposure, according to a study published online June 16 in the Journal of Clinical Endocrinology & Metabolism.

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Personal Choice of Diet Plan May Lead to Less Weight Loss

TUESDAY, June 16, 2015 (HealthDay News) -- Choosing a weight-loss plan based on food preferences might backfire and lead to less weight loss, according to a study published in the June 16 issue of the Annals of Internal Medicine.

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Review Examines Inappropriate Prescribing of IV Fluids

TUESDAY, June 16, 2015 (HealthDay News) -- Inappropriate prescribing of intravenous (IV) fluids most often involves incorrect volumes and types of IV fluids prescribed, according to a review published online June 11 in the Journal of Clinical Pharmacy and Therapeutics.

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Testosterone + Fenofibrate Yields Strongest Effect on Cardio Risks

TUESDAY, June 16, 2015 (HealthDay News) -- A combination of testosterone and fenofibrate may offer men with high cholesterol and late-onset hypogonadism the most cardiometabolic benefit, according to a study published online May 29 in Cardiovascular Therapeutics.

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Article Weighs Paying Off Student Loans Versus Investment

MONDAY, June 15, 2015 (HealthDay News) -- Newly-minted physicians should consider the issues relating to paying off their loans versus investing for retirement, according to an article published in Medical Economics.

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Low Serum 25(OH)D3 in Patients Newly Diagnosed With T2DM

MONDAY, June 15, 2015 (HealthDay News) -- Serum 25-hydroxyvitamin D3 (25[OH]D3) is associated with glucose-stimulated insulin secretion and β-cell function in individuals with newly diagnosed type 2 diabetes, according to a study published online June 5 in the Journal of Diabetes Investigation.

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Physical Activity Inversely Tied to Hypoglycemia With Coma in T1DM

FRIDAY, June 12, 2015 (HealthDay News) -- For patients with type 1 diabetes, regular physical activity (PA) is beneficial for glycemic control, diabetes-linked comorbidities, and cardiovascular risk factors, without apparent increase in adverse events, according to a study published online May 26 in Diabetes Care.

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Some Graduating Seniors Not Matching to Residency Positions

THURSDAY, June 11, 2015 (HealthDay News) -- More than 250 of this year's graduating seniors from U.S. medical schools did not match to a residency position, according to the American Medical Association.

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β-Cell Function Linked to Inflammation in PCOS

THURSDAY, June 11, 2015 (HealthDay News) -- For women with polycystic ovary syndrome (PCOS), pancreatic β-cell dysfunction is associated with hyperglycemia-induced nuclear factor-κB (NF-κB) activation and systemic inflammation, according to a study published in the May 1 issue of the American Journal of Physiology-Endocrinology and Metabolism.

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Report Offers Guidance on Medical Ethics Education

WEDNESDAY, June 10, 2015 (HealthDay News) -- An analysis of the current state of medical ethics education in the United States has been published in the June issue of Academic Medicine. The article, the Romanell Report, also offers guidance to assist medial ethics educators in meeting expectations.

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Geographic Location Most Important for Residents

WEDNESDAY, June 10, 2015 (HealthDay News) -- For residents, the most important element in a future practice is geographic location, with lifestyle, adequate call hours and personal time, and a good financial package also cited as being important, according to the American Medical Association (AMA).

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Extra Time During MCAT Linked to Less Success in Med School

WEDNESDAY, June 10, 2015 (HealthDay News) -- Medical school applicants with Medical College Admission Test (MCAT) scores obtained with extra test administration time have lower rates of success in medical schools, according to a study published in the June 9 issue of the Journal of the American Medical Association.

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Review Explores Effect of Sulfonylureas on Lipids in T2DM

TUESDAY, June 9, 2015 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), sulfonylureas seem to increase levels of free fatty acids (FFA) and triglycerides (TG) and lower low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), according to a meta-analysis published online June 4 in the Journal of Evidence-Based Medicine.

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Analysis Targets U.S. Hospitals With Highest Markups

TUESDAY, June 9, 2015 (HealthDay News) -- The 50 U.S. hospitals with the highest charge-to-cost ratio have markups approximately 10 times the Medicare-allowable costs, and most of these hospitals are for profit, according to a study published in the June issue of Health Affairs.

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AMA Offers Guidance for Physician-Hospital Relationships

MONDAY, June 8, 2015 (HealthDay News) -- New guidelines can enable successful physician hospital relationships and integrated leadership, according to a report published by the American Medical Association (AMA).

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25(OH)D Inversely Linked to Arterial Stiffness in Some Teens

MONDAY, June 8, 2015 (HealthDay News) -- In lean adolescents and in obese adolescents with type 2 diabetes (T2DM), but not obese adolescents with normoglycemia, 25-hydroxyvitamin D (25[OH]D) is inversely associated with some measures of arterial stiffness, according to a study published online May 26 in Diabetes Care.

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Internet-Based Videoconference Viable for Teen T1DM Therapy

MONDAY, June 8, 2015 (HealthDay News) -- Adolescents with poor glycemic control of their type 1 diabetes can benefit from therapy delivered either via face to face sessions or videoconferencing, according to a study published online June 1 in Diabetes Care.

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Time-Updated Hemoglobin A1c Variables Linked to MI Risk

FRIDAY, June 5, 2015 (HealthDay News) -- Time-updated hemoglobin A1c (HbA1c) variables have a stronger association with myocardial infarction (MI) than baseline HbA1c, according to a study published online May 26 in Diabetes Care.

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UWF Retinal Imaging Process Could Reduce Practice Burden

FRIDAY, June 5, 2015 (HealthDay News) -- Real-time ultrawide field (UWF) retinal image evaluation by nonphysician imagers can accurately detect diabetic retinopathy (DR) and help reduce center image grading burden, according to a study published online June 1 in Diabetes Care.

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Obesity Has Negative Impact on Metabolic Quality of Muscle

FRIDAY, June 5, 2015 (HealthDay News) -- Among older men, obesity has a negative effect on the metabolic quality of skeletal muscle, according to a study published online May 26 in Diabetes.

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Gastritis Linked to Metformin-Related GI Side Effects in T2DM

FRIDAY, June 5, 2015 (HealthDay News) -- For patients with type 2 diabetes, asymptomatic gastritis is associated with metformin-related gastrointestinal side effects, according to a study published online May 29 in the Journal of Clinical Pharmacy and Therapeutics.

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Intensive Glycemic Control May Ward Off Cardiovascular Events

THURSDAY, June 4, 2015 (HealthDay News) -- Intensive glycemic control appears to reduce cardiovascular events in patients with type 2 diabetes, according to a study published in the June 4 issue of the New England Journal of Medicine.

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Hyperhomocysteinemia Linked to Worse Cognitive Status

THURSDAY, June 4, 2015 (HealthDay News) -- For older adults, hyperhomocysteinemia is associated with worse cognitive status, even after accounting for B group vitamin (BGV) status, according to a study published online June 1 in the Journal of the American Geriatrics Society.

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Interstate Medical Licensure Compact Formed

THURSDAY, June 4, 2015 (HealthDay News) -- Nine states have enacted the Interstate Medical Licensure Compact law, with the seventh state's enactment triggering formation of a commission to administer a process for physicians seeking licensure in multiple states, according to a report published by the American Academy of Family Physicians.

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NASH-Linked Changes Impact Metformin Pharmacokinetics

THURSDAY, June 4, 2015 (HealthDay News) -- Nonalcoholic steatohepatitis (NASH)-associated changes in liver function affect kidney transporter expression and metformin pharmacokinetics, according to an experimental study published online May 27 in Diabetes Care.

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Metabolic Syndrome Up With ADT in Prostate Cancer

THURSDAY, June 4, 2015 (HealthDay News) -- For patients with prostate cancer treated with androgen deprivation therapy there are increases in components of metabolic syndrome and in the prevalence of full metabolic syndrome, according to a study published in the June issue of The Journal of Urology.

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CMS: Hospital Charges for Common Procedures Up

WEDNESDAY, June 3, 2015 (HealthDay News) -- The prices hospitals charge patients for a number of common procedures rose more than 10 percent between 2011 and 2013, more than twice the rate of inflation, according to data released by the federal government Monday.

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24-Hour Diastolic BP Linked to Cognitive Performance in T2DM

WEDNESDAY, June 3, 2015 (HealthDay News) -- Among individuals with type 2 diabetes there is a quadratic association for 24-hour diastolic blood pressure (BP) with information processing speed and memory, according to a study published online May 27 in Diabetes Care.

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Therapy Program Improves Teens' Diabetes, Depression

WEDNESDAY, June 3, 2015 (HealthDay News) -- The evidence-based family therapy program Behavioral Family Systems Therapy for Diabetes (BFST-D) improves both diabetes health outcomes and depressive symptoms among adolescents with type 1 diabetes, according to a study published online May 26 in Diabetes Care.

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T2DM May Help Protect Against Amyotrophic Lateral Sclerosis

TUESDAY, June 2, 2015 (HealthDay News) -- Type 2 diabetes may reduce the risk of developing amyotrophic lateral sclerosis (ALS), according to a new report published online June 1 in JAMA Neurology.

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Women With HTN, Diabetes Less Likely to Use Alternative Rx

TUESDAY, June 2, 2015 (HealthDay News) -- Women with hypertension and diabetes are less likely to consult with a complementary and alternative medicine (CAM) practitioner and to self-prescribe CAM, according to a study published in the June 15 issue of The American Journal of Cardiology.

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Review: Diet-Linked Weight Loss Tied to Drop in Hip BMD

MONDAY, June 1, 2015 (HealthDay News) -- Diet-induced weight loss is associated with a decrease in total hip, but not lumbar spine, bone mineral density (BMD), according to a review published online May 25 in the Journal of Bone and Mineral Research.

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