Acquire the license to the best health content in the world
Contact Us

May 2009 Briefing - Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for May 2009. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Signaling Pathway Mediates Steroid-Induced Diabetes

THURSDAY, May 28 (HealthDay News) -- Steroid-induced pancreatic β-cell dysfunction and diabetes mellitus are mediated through a cellular signaling pathway that, when blocked, can restore β-cell function, according to a study published online May 14 in Endocrinology.

Abstract
Full Text (subscription or payment may be required)

Childhood Type 1 Diabetes Set to Double in Europe by 2020

THURSDAY, May 28 (HealthDay News) -- Childhood type 1 diabetes cases are on the rise in Europe, and are set to double among the under-fives by 2020 compared to 2005, according to a study published online on May 28 in The Lancet.

Abstract
Full Text (subscription or payment may be required)

Computerized Prescription Order Errors a Risk for Patients

THURSDAY, May 28 (HealthDay News) -- Computerized provider order entry systems are prone to input errors that may put patients at risk, according to a study published in the May 25 issue of the Archives of Internal Medicine.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Focus on Meaningful Work Protects Doctors From Burnout

THURSDAY, May 27 (HealthDay News) -- Academic faculty physicians who focus on what they find most meaningful are less likely to experience burnout, according to a study published in the May 25 issue of the Archives of Internal Medicine.

Abstract
Full Text (subscription or payment may be required)

Better Rat Model of Epilepsy in Women Developed

WEDNESDAY, May 27 (HealthDay News) -- A better animal model of epilepsy in women has been developed where the animals retain reproductive function, which may allow better study of epilepsy where seizures occur during specific stages of the menstrual cycle, according to a study published online May 14 in Endocrinology.

Abstract
Full Text (subscription or payment may be required)

Gene Finding May Influence Kidney Transplant Outcomes

WEDNESDAY, May 27 (HealthDay News) -- Kidney transplant recipients who have T allelic variants in exons 21 or 26 of the ABCB1 gene may have a greater likelihood of several adverse events related to cyclosporine A, according to research published online May 21 in the Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)

U.K. Initiative Has Unclear Effects on Diabetes Care

WEDNESDAY, May 27 (HealthDay News) -- Since the late 1990s, the management of diabetes has improved in the United Kingdom, but it may not be a direct result of the quality and outcomes framework introduced in 2004, according to a study published online May 27 in BMJ.

Abstract
Full Text

Obese and Diabetic Youth Have Carotid Abnormalities

WEDNESDAY, May 27 (HealthDay News) -- Young people who are obese or who have type 2 diabetes mellitus have abnormalities in the carotid artery that should serve as an alert to increased risk of stroke and myocardial infarction in adulthood, according to a study published online on May 26 in Circulation.

Abstract
Full Text (subscription or payment may be required)

Balance Dysfunction Common in American Adults

TUESDAY, May 26 (HealthDay News) -- Disrupted balance as a result of vestibular dysfunction is common among American adults and is a significant contributor to the incidence of falls, according to a study published in the May 25 issue of the Archives of Internal Medicine.

Abstract
Full Text (subscription or payment may be required)

Triglyceride Level Associated with Diabetic Neuropathy

TUESDAY, May 26 (HealthDay News) -- The progression of diabetic neuropathy is associated with elevated triglycerides in the blood and with decreased conduction of the peroneal motor nerve, according to a study published online May 1 in Diabetes.

Abstract
Full Text (subscription or payment may be required)

Gestational Diabetes Provides a Chance to Educate Patients

TUESDAY, May 26 (HealthDay News) -- Because women with gestational diabetes are at increased risk of subsequently developing type 2 diabetes, increasing awareness among both physicians and patients about the risk can be used as an opportunity to promote behavior that may delay or prevent the disease, according to a study published in the May 23 issue of The Lancet.

Abstract
Full Text (subscription or payment may be required)
Editorial
Comment

Daily Glucose Self-Monitoring May Reduce Macrosomia Risk

MONDAY, May 25 (HealthDay News) -- Daily glucose self-monitoring in women with diet-treated gestational diabetes may be associated with a lower risk of delivering an oversized infant than routine weekly monitoring, according to research published in the June issue of Obstetrics & Gynecology.

Abstract
Full Text (subscription or payment may be required)

Telemedicine Benefits Children With Type 1 Diabetes

FRIDAY, May 22 (HealthDay News) -- In children with type 1 diabetes, a school-based telemedicine program may lead to better outcomes, according to a study published online May 22 in the Journal of Pediatrics.

Abstract
Full Text (subscription or payment may be required)

Intensive Glucose Lowering Reduces Diabetics' Heart Risks

FRIDAY, May 22 (HealthDay News) -- In patients with type 2 diabetes, an intensive glucose-lowering regimen significantly reduces coronary events without increasing the risk of death, according to a study published in the May 23 issue of The Lancet.

Abstract
Full Text (subscription or payment may be required)

Fenofibrate May Help Prevent Amputations in Diabetics

FRIDAY, May 22 (HealthDay News) -- In patients with type 2 diabetes, fenofibrate may lower the risk of minor amputation, according to a study published in the May 23 issue of The Lancet.

Abstract
Full Text (subscription or payment may be required)

Turmeric Component Reduces Weight Gain in Obesity Model

FRIDAY, May 22 (HealthDay News) -- A component of the spice turmeric blocks the growth and development of fat cells and reduces weight gain in a mouse model of obesity, according to a study in the May issue of the Journal of Nutrition.

Abstract
Full Text (subscription or payment may be required)

Cellular Pathway Mediates Longevity Due to Diet

FRIDAY, May 22 (HealthDay News) -- A component of a nutrient-sensing cellular signaling pathway plays an important role in the increased lifespan resulting from dietary restriction, according to a study published online May 22 in PLoS Genetics.

Full Text

Overnight Hemodialysis Improves Urea Reduction

THURSDAY, May 21 (HealthDay News) -- Compared to conventional four- to five-hour hemodialysis, long overnight dialysis lasting six to seven hours results in a better urea reduction ratio and less anemia, according to a study published online on May 21 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)

Breast Tumors Linked to Depression and Anxiety

THURSDAY, May 21 (HealthDay News) -- The mere presence of breast tumors in rats is associated with depression and anxiety, according to a study published online May 18 in the Proceedings of the National Academy of Sciences.

Abstract
Full Text (subscription or payment may be required)

Democrats Set Ambitious Goal for Health Care Reform

THURSDAY, May 21 (HealthDay News) -- Congressional Democrats face formidable challenges in their efforts to pass health care reform legislation by July 31, but physicians can take the lead to ensure changes are enacted, according to two perspectives published online May 20 in the New England Journal of Medicine.

Full Text - Iglehart
Full Text - Fisher

Statins May Cut Liver Cancer and Cholecystectomy Risks

THURSDAY, May 21 (HealthDay News) -- Statin use is associated with reduced risk for cholecystectomy and for liver cancer, according to two studies published in the May issue of Gastroenterology.

Abstract - Tsai
Full Text (subscription or payment may be required)
Abstract - El-Serag
Full Text (subscription or payment may be required)

Pregnancy Linked to Poorer Thyroid, Parathyroid Outcomes

THURSDAY, May 21 (HealthDay News) -- Pregnant women who undergo thyroid or parathyroid surgery are more likely to have worse clinical outcomes than non-pregnant women in terms of complications and length of stay, according to research published in the May issue of the Archives of Surgery.

Abstract
Full Text

ARBs Found Ineffective for Renal Function in Diabetes

THURSDAY, May 21 (HealthDay News) -- Two angiotensin receptor blockers are ineffective in reducing renal dysfunction in patients at high risk of vascular disease such as diabetics, according to two studies published online May 19 in the Annals of Internal Medicine.

Abstract - Mann
Full Text
Abstract - Bilous
Full Text

Sticking to Work Hours Limits Very Costly

WEDNESDAY, May 20 (HealthDay News) -- Adherence to the 2003 Accreditation Council for Graduate Medical Education (ACGME) limits on work hours, and other measures aimed at reducing fatigue among residents, would be costly with no proven benefits, according to an article published in the May 21 issue of the New England Journal of Medicine.

Abstract
Full Text (subscription or payment may be required)
Editorial

Dipyridamole Can Cut Risk of Hemodialysis Stenosis

WEDNESDAY, May 20 (HealthDay News) -- A combination of aspirin and dipyridamole can yield a modest reduction in the risk of arterovenous graft stenosis in patients undergoing hemodialysis, and can increase the duration of patency in new grafts, according to a study published in the May 21 issue of the New England Journal of Medicine.

Abstract
Full Text (subscription or payment may be required)
Editorial

Antihypertensive Drugs Also Benefit Non-Hypertensives

WEDNESDAY, May 20 (HealthDay News) -- In everyone at risk for heart attack or stroke -- including those with normal blood pressure -- antihypertensive treatment significantly reduces the risk of coronary heart disease events and stroke, according to a study published online May 19 in BMJ.

Abstract
Full Text
Editorial

Personalized Support Helps Improve Diet and Fitness

WEDNESDAY, May 20 (HealthDay News) -- An e-mail-based intervention with personalized content can help people eat more healthily and do more physical activity, according to a study published online May 19 in the American Journal of Preventive Medicine.

Abstract
Full Text (subscription or payment may be required)

Fast Weight Decline in Old Age May Increase Dementia Risk

TUESDAY, May 19 (HealthDay News) -- Higher body mass index (BMI) late in life is associated with a lowered risk of developing dementia with further aging, according to a study reported in the May 19 issue of Neurology.

Abstract
Full Text (subscription or payment may be required)

Adolescent Testosterone Enhances Adult Mating

MONDAY, May 18 (HealthDay News) -- Elevated testosterone before and during adolescence enhances male mating behavior in adulthood, while increased testosterone before adolescence affects the size of various brain areas associated with mating behavior in juveniles, according to a study published online May 7 in Endocrinology.

Abstract
Full Text (subscription or payment may be required)

Hypoglycemia More Common in Chronic Kidney Disease

THURSDAY, May 14 (HealthDay News) -- Patients with chronic kidney disease (CKD) may be at higher risk of hypoglycemia, even in the absence of diabetes, according to research published online May 7 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text

Hypothyroidism Linked to Liver Cancer in Women

THURSDAY, May 14 (HealthDay News) -- Hypothyroidism is associated with a three-fold higher risk of developing liver cancer in women, even among those without major risk factors, according to a study in the May issue of Hepatology.

Abstract
Full Text

More Exercise May Provide Greater Gains in Heart Disease

THURSDAY, May 14 (HealthDay News) -- A program featuring greater amounts of exercise and energy expenditure may be preferable to standard cardiac rehabilitation exercise in overweight patients with coronary heart disease, according to research published online May 11 in Circulation.

Abstract
Full Text (subscription or payment may be required)

Diabetes Linked to Death After a Heart Attack

WEDNESDAY, May 13 (HealthDay News) -- Patients who have had a heart attack have a higher risk of death or hospitalization for heart failure if they have diabetes mellitus, according to a study in the May issue of JACC: Cardiovascular Imaging.

Abstract
Full Text (subscription or payment may be required)
Editorial

Women Are Forgoing Health Care More Than Men

WEDNESDAY, May 13 (HealthDay News) -- Cost-related access problems disproportionately affect women, with 52 percent in 2007 reporting problems gaining access to the heath care they needed, compared with 39 percent of men, according to a report published May 11 by The Commonwealth Fund.

Abstract
Full Text

Antioxidants Block Beneficial Effects of Exercise

TUESDAY, May 12 (HealthDay News) -- Oxidative stress resulting from exercise increases insulin sensitivity and promotes the body's own antioxidant defense, a response that is blocked by taking antioxidants such as vitamin C, according to a study published online May 11 in the Proceedings of the National Academy of Sciences.

Abstract
Full Text

Kidney Disease Preventive Care Linked to Heart Protection

MONDAY, May 11 (HealthDay News) -- People with chronic kidney disease (CKD) who receive preventive care may have a lower risk of cardiovascular mortality and morbidity, according to research published online May 7 in the Journal of the American Society of Nephrology.

Abstract
Full Text

Diabetes Drug Reduces Insulin Secretion of β-Cells

MONDAY, May 11 (HealthDay News) -- The antidiabetic drug pioglitazone may preserve pancreatic β-cell function by reducing insulin secretion at intermediate glucose concentrations and reducing the energy metabolism of the cells, according to a study published online April 30 in Endocrinology.

Abstract
Full Text (subscription or payment may be required)

Calorie-Restricted Diet Improves Insulin Sensitivity

MONDAY, May 11 (HealthDay News) -- Calorie-restricted (CR) diets initially alter the insulin sensitivity of the liver and only later change the insulin sensitivity of muscles as the body adapts to the reduced caloric intake, according to a study published in the May issue of Gastroenterology.

Abstract
Full Text (subscription or payment may be required)

Monthly Testosterone Effective as a Male Contraceptive

FRIDAY, May 8 (HealthDay News) -- Monthly injections of testosterone can provide effective reversible contraception for healthy fertile men without adverse effects, according to a study first published online on March 17 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
Full Text (subscription or payment may be required)

Visceral Fat-Depression Link Explored in Women

WEDNESDAY, May 6 (HealthDay News) -- Middle-aged women with depression tend to have more visceral fat than their nondepressed counterparts, which could explain why they are at higher risk for diabetes and cardiovascular disease, according to a study published online April 27 in Psychosomatic Medicine.

Abstract
Full Text (subscription or payment may be required)

Medical Center Press Releases Often Lacking Key Details

TUESDAY, May 5 (HealthDay News) -- Press releases from academic medical centers may often overstate the importance of research findings while failing to acknowledge relevant limitations of the studies, according to research published in the May 5 Annals of Internal Medicine.

Full Text

Pancreas Graft Function Affects Survival in Diabetics

MONDAY, May 4 (HealthDay News) -- Patients with type 1 diabetes and severe renal dysfunction who receive a simultaneous pancreas-kidney transplant have better survival if the pancreas remains functional a year after the transplant, according to a study published online ahead of print April 30 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)

Progesterone Activator Involved in Endometriosis

MONDAY, MAY 4 (HealthDay News) -- Women with endometriosis have impaired expression and cycle-dependent regulation of a progesterone receptor co-activator, which may explain progesterone resistance in endometrium from these women, according to a study published online April 23 in Endocrinology.

Abstract
Full Text (subscription or payment may be required)

Income, Education Associated With Diet Cost and Quality

MONDAY, May 4 (HealthDay News) -- People with higher socioeconomic status and educational levels are more likely to consume a costly but high-quality diet of lower-energy-density foods, according to a study published in the May issue of the Journal of the American Dietetic Association.

Abstract
Full Text (subscription or payment may be required)

Wrong Approach to Obesity Can Alienate Patients

FRIDAY, May 1 (HealthDay News) -- When physicians tackle the issue of obesity with their black patients, they may unintentionally alienate them if they do not use the right timing and approach, according to a study published in the May issue of the Journal of General Internal Medicine.

Abstract
Full Text (subscription or payment may be required)

More Americans Reporting Disability

FRIDAY, May 1 (HealthDay News) -- The number of Americans reporting disabilities rose by 7.7 percent from 44.1 million in 1999 to 47.5 million in 2005, according to a report in the May 1 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

More Information

Physician's Briefing