See What HealthDay Can Do For You
Contact Us

May 2010 Briefing - Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for May 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Higher Varicocele Grade Linked to Lower Sperm Density

FRIDAY, May 28 (HealthDay News) -- In men with varicocele and infertility, the grade of the varicocele is related to semen quality, and grade III varicoceles are associated with higher testosterone levels, according to research published in the May issue of Urology.

Abstract
Full Text (subscription or payment may be required)

Cardiac Event Biomarker Linked to Volume Overload

FRIDAY, May 28 (HealthDay News) -- Among stable hemodialysis patients, N-terminal probrain type natriuretic peptide (NTproBNP) may not be associated with cardiac dysfunction but appears to be dependent on factors associated with volume overload, and may also be elevated in those with malnutrition, according to a study published online May 27 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Baseline DPP-IV Not Found to Predict Incident Diabetes

FRIDAY, May 28 (HealthDay News) -- Fasting levels of dipeptidyl peptidase IV (DPP-IV) don't appear to predict later diabetes, according to research published in the May issue of Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

In Diabetes Patients at Low CVD Risk, Aspirin Not Recommended

THURSDAY, May 27 (HealthDay News) -- Low-dose aspirin for prevention of cardiovascular disease (CVD) is reasonable for adults with diabetes who are at increased CVD risk but should not be routinely recommended for those at low CVD risk, according to a combined statement from the American Diabetes Association, the American Heart Association, and the American College of Cardiology Foundation, published online May 27 in Circulation, Diabetes Care, and the Journal of the American College of Cardiology.

Abstract
Full Text (subscription or payment may be required)

Exenatide, Rosiglitazone Combo Beneficial in Type 2 Diabetes

THURSDAY, May 27 (HealthDay News) -- The addition of exenatide and rosiglitazone to metformin in type 2 diabetes is associated with glycemic control benefits, improvements in β-cell function and insulin sensitivity, and weight loss, according to research published in the May issue of Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

Early Glycemic Control Vital in Type 1 Diabetes

THURSDAY, May 27 (HealthDay News) -- Intense glycemic control early on should be attempted for individuals with type 1 diabetes to reduce the risk of complications related to diabetes arising over time, according to research published in the May issue of Diabetes.

Abstract
Full Text (subscription or payment may be required)

Inflammatory Biomarker Linked to CHD in Type 2 Diabetes

THURSDAY, May 27 (HealthDay News) -- The newly recognized inflammatory biomarker lipoprotein-associated phospholipase A2 (Lp-PLA2) appears to be a risk factor for coronary heart disease (CHD) in people with type 2 diabetes, according to research published in the May issue of Diabetes.

Abstract
Full Text (subscription or payment may be required)

FDA Changes Label on Weight-Loss Drug Orlistat

WEDNESDAY, May 26 (HealthDay News) -- The U.S. Food and Drug Administration has alerted health care providers and consumers regarding a label change to the weight-loss drug orlistat, marketed by prescription by F. Hoffmann-La Roche Ltd. as Xenical (orlistat 120 mg) and over-the-counter (OTC) without a prescription by GSK Consumer Healthcare as Alli (orlistat 60 mg), due to the potential but rare risk of severe liver injury.

More Information

Insulin Use May Lower Cancer Risk in Type 2 Diabetes

WEDNESDAY, May 26 (HealthDay News) -- In Chinese patients with type 2 diabetes, the use of insulin appears protective against the development of cancer, though hyperglycemia may increase cancer risk, according to research published in the May issue of Diabetes.

Abstract
Full Text (subscription or payment may be required)

Benefit Seen From High-Protein Diet, Resistance Exercise

WEDNESDAY, May 26 (HealthDay News) -- In overweight individuals with type 2 diabetes, a high-protein, restricted-energy diet in combination with resistance exercise training is associated with particular improvements in body weight and composition when compared with other approaches, according to research published in the May issue of Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

Increasing Exercise Linked to Decreasing Obesity in Women

TUESDAY, May 25 (HealthDay News) -- In adult women, there is a crude, graded inverse dose-response relationship between total volume of leisure-time physical activity and obesity, according to a study published in the May issue of the Journal of Epidemiology and Community Health.

Abstract
Full Text (subscription or payment may be required)

Frequent Doctor Visits Benefit Hypertensive Diabetes Patients

MONDAY, May 24 (HealthDay News) -- In hypertensive patients with diabetes, shorter intervals between encounters with physicians are associated with a faster decrease in blood pressure and earlier blood pressure normalization -- particularly intervals shorter than those currently recommended, according to a study published online May 24 in Hypertension.

Abstract
Full Text (subscription or payment may be required)

Metformin Associated With Decreased B-12

FRIDAY, May 21 (HealthDay News) -- Patients being treated with metformin to control their diabetes may have a higher risk of decreased levels of vitamin B-12 and increased homocysteine levels, according to research published in the May 20 online edition of the BMJ.

Abstract
Full Text

Faster Weight Loss Appears to Yield Better Results

THURSDAY, May 20 (HealthDay News) -- People who lose greater amounts of weight initially in weight-loss attempts may experience better weight loss and maintenance results than those who lose weight gradually, according to research published in the June issue of the International Journal of Behavioral Medicine.

Abstract
Full Text (subscription or payment may be required)

Vitamin D Insufficiency Common in Young Women

THURSDAY, May 20 (HealthDay News) -- Many U.S. women of childbearing age have vitamin D insufficiency, and the current recommended dosage for prenatal vitamin D supplementation may need to be increased to reach recommended levels, according to a study in the American Journal of Obstetrics & Gynecology.

Abstract
Full Text (subscription or payment may be required)

Diabetic Retinopathy Detectors Equally Effective

THURSDAY, May 20 (HealthDay News) -- A new automated detection algorithm appears to be as effective at detecting diabetic retinopathy as an established algorithm used in a large early-detection project, according to a study published online April 16 in Ophthalmology.

Abstract
Full Text (subscription or payment may be required)

Ketogenic Diet Linked to Altered Insulin Sensitivity

WEDNESDAY, May 19 (HealthDay News) -- In rats, the use of a ketogenic diet appears to negatively affect glucose homeostasis, though the effects are quickly reversed when the diet is halted, according to research published online April 28 in Endocrinology.

Abstract
Full Text (subscription or payment may be required)

In Prostate Cancer, Selective Alendronate Use Cost-Effective

TUESDAY, May 18 (HealthDay News) -- A bone mineral density test followed by selective use of alendronate for fracture prevention in men beginning androgen deprivation therapy for localized prostate cancer is cost-effective, according to research published in the May 18 issue of the Annals of Internal Medicine.

Abstract
Full Text (subscription or payment may be required)

Obesity, Diabetes Associated With Low Free Testosterone

MONDAY, May 17 (HealthDay News) -- Among obese men older than 45 years of age, 40 percent of those without diabetes and half of those with diabetes have below-normal free testosterone (FT) concentrations, according to research published online in Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

Pernicious Anemia Patients at Higher Risk for Hip Fractures

FRIDAY, May 14 (HealthDay News) -- Even after years of vitamin B-12 therapy, people with pernicious anemia are still at increased risk for hip fractures, which suggests a mechanism other than B-12 deficiency could be driving their vulnerability, according to research published in the April issue of Gastroenterology.

Abstract
Full Text (subscription or payment may be required)

Many General Internists Leave Field by Mid-Career

FRIDAY, May 14 (HealthDay News) -- Roughly one out of six general internists are leaving internal medicine by mid-career, a substantially higher proportion compared to internal medicine subspecialists, according to survey results published April 29 in the Journal of General Internal Medicine.

Abstract
Full Text (subscription or payment may be required)

Early Child Care May Affect Functioning in Teenage Years

FRIDAY, May 14 (HealthDay News) -- The quality and quantity of early child care is associated with functioning, including academic achievement, at age 15, according to a study published in the May/June issue of Child Development. Another study in the same issue found increased cortisol levels in children when they were at full-time, home-based day care versus when they were at home.

Abstract - Vandell
Full Text (subscription or payment may be required)
Abstract - Gunnar
Full Text (subscription or payment may be required)

Neuropathic Pain Increases Related Medical Costs

FRIDAY, May 14 (HealthDay News) -- Common types of neuropathic pain, such as that associated with herpes zoster or diabetes, can add substantially to health care costs related to those conditions, according to a study reported in the April issue of the Journal of Pain.

Abstract
Full Text (subscription or payment may be required)

Steps Per Day Linked to Metabolic Syndrome Prevalence

THURSDAY, May 13 (HealthDay News) -- Although public health recommendations have tended to focus on moderate-to-vigorous physical activity, an active lifestyle as measured by steps per day is associated with a reduced prevalence of both metabolic syndrome (MetS) and its cardiovascular disease (CVD) risk factors, according to research published online May 4 in the American Journal of Preventive Medicine.

Full Text

Removing Financial Incentives May Reduce Performance

WEDNESDAY, May 12 (HealthDay News) -- The focus of clinicians may change and their performance levels could drop when previously established financial incentives are removed, according to research published May 11 in BMJ.

Abstract
Full Text

New FDA Program Targets Misleading Drug Advertising

WEDNESDAY, May 12 (HealthDay News) -- The U.S. Food and Drug Administration has announced the launch of a new program to educate health care providers regarding their role in making certain that advertisements and promotions for prescription drugs are truthful and not misleading.

badad@fda.gov
More Information

High BMI Partly Explains Family-Based Diabetes Risk

WEDNESDAY, May 12 (HealthDay News) -- A high body mass index (BMI) and, to some extent, specific lifestyle factors may explain a substantial part of the association between family history of diabetes and type 2 diabetes risk, according to research published in the April issue of Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

High-Dose Vitamin D Linked to Falls, Fractures in Women

TUESDAY, May 11 (HealthDay News) -- Older women receiving an annual large dose of vitamin D may have an increased risk of falls and fractures, according to research published in the May 12 issue of the Journal of the American Medical Association.

Abstract
Full Text
Editorial (subscription or payment may be required)

In Women With Diabetes, More Bran Tied to Lower Mortality

MONDAY, May 10 (HealthDay News) -- Increasing dietary whole grains, especially the bran component, is linked to decreased all-cause and cardiovascular disease-specific mortality in women with type 2 diabetes, according to a study published online May 10 in Circulation.

Abstract
Full Text (subscription or payment may be required)

Many Youths With Diabetes Get Too Little Exercise

MONDAY, May 10 (HealthDay News) -- Many youths with diabetes mellitus (DM), especially males with type 2 disease, do not meet recommendations for physical activity and electronic media use, according to a study published online May 10 in Pediatrics.

Abstract
Full Text (subscription or payment may be required)

Single Night of Lost Sleep Implicated in Insulin Resistance

MONDAY, May 10 (HealthDay News) -- A single night of little sleep can cause metabolic abnormalities including insulin resistance, according to research published online April 6 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
Full Text (subscription or payment may be required)

Microalbuminuria Can Predict Complications in Hypertension

FRIDAY, May 7 (HealthDay News) -- Microalbuminuria independently predicts higher risk of renal and cardiovascular complications in patients with primary hypertension but without diabetes, according to research published online April 29 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)

Autonomous Motivation May Have Large Role in Weight Loss

FRIDAY, May 7 (HealthDay News) -- Autonomous motivation is a potential intervention target for increasing adherence to self-monitoring in a weight-loss program and weight loss itself, according to a study published in the May 2010 issue of the Journal of Nutrition Education and Behavior.

Abstract
Full Text (subscription or payment may be required)

Preconception Counseling Benefits Teens With Diabetes

THURSDAY, May 6 (HealthDay News) -- A preconception counseling program aimed at female teenagers with type 1 diabetes is beneficial and cost-effective, and its effects are sustained for at least nine months, according to research published in the April issue of Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

Seminar Addresses State of Childhood Obesity

THURSDAY, May 6 (HealthDay News) -- Although the rapid increase in childhood obesity prevalence in developed countries may be stabilizing, rates have risen substantially since the 1970s, and efforts to prevent obesity should continue at all levels, though bariatric surgery should be used only as a last-resort treatment in extreme cases, according to a seminar published online May 6 in The Lancet.

Abstract
Full Text (subscription or payment may be required)

Everolimus-Eluting Superior to Paclitaxel-Eluting Stent

WEDNESDAY, May 5 (HealthDay News) -- Coronary everolimus-eluting stents result in superior clinical outcomes compared with paclitaxel-eluting stents, and reduced rates of target-lesion failure at one year seen with everolimus-eluting stents are consistent in all patients except those with diabetes, according to research published in the May 6 issue of the New England Journal of Medicine.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Prognosis Varies Per Glycemic Index Pre-Revascularization

WEDNESDAY, May 5 (HealthDay News) -- Having a low -- but not too low -- glycemic index prior to surgery is optimal for best cardiovascular outcomes after coronary revascularization in patients with type 2 diabetes mellitus (DM), according to a study in the April 1 issue of the American Journal of Cardiology.

Abstract
Full Text (subscription or payment may be required)

Growth Hormone Enhances Body Composition in Athletes

TUESDAY, May 4 (HealthDay News) -- Giving growth hormone to recreational athletes -- alone in women and alone or with testosterone in men -- results in increased sprint capacity and changes in body composition, according to a study in the May 4 issue of the Annals of Internal Medicine.

Abstract
Full Text (subscription or payment may be required)

Rate of Childhood Obesity, Overweight Varies by State

MONDAY, May 3 (HealthDay News) -- In 2007, there were substantial geographic disparities in childhood overweight and obesity, with the prevalence increasing in many states from 2003 to 2007, according to data published online May 3 in the Archives of Pediatrics & Adolescent Medicine.

Abstract
Full Text (subscription or payment may be required)

Physician's Briefing

HealthDay

HealthDay is the world’s largest syndicator of health news and content, and providers of custom health/medical content.

Consumer Health News

A health news feed, reviewing the latest and most topical health stories.

Professional News

A news feed for Health Care Professionals (HCPs), reviewing latest medical research and approvals.