Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for November 2006. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Coffee Use Associated with Lower Diabetes Risk
THURSDAY, Nov. 30 (HealthDay News) -- Coffee drinking is associated with a lower risk of developing diabetes, even in people with impaired glucose, researchers report in the November issue of Diabetes Care.
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Over Half of Obese Teens Are Insulin Resistant
THURSDAY, Nov. 30 (HealthDay News) -- Some 52.1 percent of obese adolescents are insulin resistant, according to the results of a population-based study published in the November issue of Diabetes Care.
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Left Ventricle Size, Function Linked to Risk Factors
THURSDAY, Nov. 30 (HealthDay News) -- Modifiable cardiovascular risk factors are associated with subclinical changes in left ventricular geometry and function as measured by magnetic resonance imaging, researchers report in the Dec. 5 issue of the Journal of the American College of Cardiology. For example, smokers and diabetics without cardiovascular disease have higher left ventricular mass, lower stroke volume and lower ejection fractions than other patients.
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Pioglitazone Benefits Nonalcoholic Steatohepatitis
WEDNESDAY, Nov. 29 (HealthDay News) -- A hypocaloric diet plus pioglitazone significantly improves glucose tolerance and liver function in patients with nonalcoholic steatohepatitis, according to the results of a proof-of-concept study reported in the Nov. 30 issue of the New England Journal of Medicine.
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Heart Attack Care Substandard in Medicaid Patients
FRIDAY, Nov. 24 (HealthDay News) -- Among patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS), those on Medicaid receive lower-quality care and experience worse outcomes than those with HMOs or private insurance, according to study findings published in the Nov. 21 issue of the Annals of Internal Medicine.
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Younger Stroke Survivors Face Health Care Barriers
MONDAY, Nov. 20 (HealthDay News) -- Younger stroke survivors may have less access to medical care, medications and health insurance than their counterparts who are 65 and older, according to study findings published online Nov. 13 in the Archives of Neurology.
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Correcting Anemia in Kidney Disease May Not Be Beneficial
THURSDAY, Nov. 16 (HealthDay News) -- For patients with chronic kidney disease, fully correcting anemia may increase the risk of adverse events, according to two studies published in the Nov. 16 issue of the New England Journal of Medicine.
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Lifestyle Changes Cut Type 2 Diabetes in High-Risk People
THURSDAY, Nov. 16 (HealthDay News) -- Intensive diet and exercise counseling can reduce disease incidence for patients at high risk of type 2 diabetes mellitus, even long after counseling is discontinued, according to results from an extended follow-up the Finnish Diabetes Prevention Study published in the Nov. 11 issue of The Lancet.
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Midlife Self-Care Extends Men's Life Span into 80s, 90s
WEDNESDAY, Nov. 15 (HealthDay News) -- Middle-aged men who avoid common risk factors for chronic disease have a better chance of achieving an "exceptional" survival, defined as living to age 85 and beyond without physical or mental impairment, according to a study published in the Nov. 15 issue of the Journal of the American Medical Association.
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Paclitaxel-Coated Balloon Catheter Reduces Restenosis
TUESDAY, Nov. 14 (HealthDay News) -- In patients with coronary in-stent restenosis, treatment with paclitaxel-coated balloon catheters may significantly reduce the risk of restenosis, according to a study published online Nov. 13 in the New England Journal of Medicine.
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More People Could Benefit from Statins
MONDAY, Nov. 13 (HealthDay News) -- A greater number of people could benefit from statins, and widening the pool of candidates for the drug would be cost-effective, according to the results of a study published online Nov. 10 in BMJ.
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Lifestyle History Affects Men's Cancer Survival
FRIDAY, Nov. 10 (HealthDay News) -- In men newly diagnosed with cancer, overall survival is significantly affected by a history of smoking, heavy alcohol consumption or insulin resistance, but not by a history of obesity, according to a study published in the Nov. 1 issue of the Journal of Clinical Oncology.
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Adiponectin Affects Periovulatory Remodeling
FRIDAY, Nov. 10 (HealthDay News) -- Adiponectin stimulates expression of genes in ovarian cells that may contribute to periovulatory remodeling, according to a report in the November issue of Endocrinology. Lower adiponectin levels found in overweight women might contribute to ovarian dysfunction that often accompanies obesity, the authors note.
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Human Stem Cells Lower Blood Glucose in Diabetic Mice
THURSDAY, Nov. 9 (HealthDay News) -- Human stem cells from bone marrow can lower blood glucose and boost the secretion of mouse insulin in diabetic mice, according to a report published online Nov. 6 in the Proceedings of the National Academy of Sciences.
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Inhaled Insulin Safe and Effective Alternative to Shots
TUESDAY, Nov. 7 (HealthDay News) -- Inhaled insulin is a safe and effective alternative to injections for pre-meal insulin administration, according to a meta-analysis of randomized, controlled trials published in the Nov. 7 issue of the Annals of Internal Medicine.
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Anabolic Steroids Linked to Criminal Activity
MONDAY, Nov. 6 (HealthDay News) -- Use of anabolic androgenic steroids may be associated with an increased risk for criminal activity, according to a report in the November issue of the Archives of General Psychiatry.
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Uric Acid Protects Endothelium in Diabetics, Smokers
MONDAY, Nov. 6 (HealthDay News) -- Uric acid can improve endothelial function in type 1 diabetics and regular smokers, possibly through its antioxidant properties, according to a report in the November issue of Diabetes.
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Obesity at Age 10 Linked to Earlier Puberty in Boys
MONDAY, Nov. 6 (HealthDay News) -- Body mass index (BMI) in 10-year-old boys is a significant predictor of age at puberty, with each unit increase in BMI linked to a 6-week reduction in the age of peak height velocity, researchers report in the November issue of Diabetes. In addition, an early puberty is associated with a central fat distribution in young adulthood.
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Gender Difference Seen in Acute Coronary Syndrome
MONDAY, Nov. 6 (HealthDay News) -- In patients with acute coronary syndrome, men are more likely to present with excessive sweating, or diaphoresis, while women are more likely to present with nausea, according to the results of a study published in the November issue of the American Journal of Cardiology.
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Poor Vision Remains Undertreated in Adult Diabetics
FRIDAY, Nov. 3 (HealthDay News) -- More than 10 percent of adult diabetics who are not blind in one or both eyes have some sort of vision impairment, and two-thirds of those could be easily corrected with proper spectacle or contact lens prescription, according to a report in the Nov. 3 issue of the Morbidity and Mortality Weekly Report.
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Intensive Insulin Therapy May Reduce ICU Deaths
FRIDAY, Nov. 3 (HealthDay News) -- Intensive insulin therapy reduces mortality in patients in the intensive care unit (ICU), except for those with diabetes or those staying in the ICU for short periods, according to a report in the November issue of Diabetes.
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Physical Activity Improves Glucose Tolerance in Pregnancy
FRIDAY, Nov. 3 (HealthDay News) -- Women who engage in vigorous physical activity before pregnancy and at least light-to-moderate activity during pregnancy are the least likely to develop gestational diabetes mellitus, suggesting a link between physical activity and glucose tolerance, according to a study published in the November issue of Obstetrics & Gynecology.
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Lower Body Temperature May Extend Life Span
THURSDAY, Nov. 2 (HealthDay News) -- Researchers have found that mice with a core temperature one-half a degree Celsius lower than normal live about 15 percent longer than mice with a normal body core temperature, according to a report in the Nov. 3 issue of Science.
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Tall Patients Have Higher Risk of Peripheral Neuropathy
THURSDAY, Nov. 2 (HealthDay News) -- Diabetics are twice as likely as non-diabetics to develop peripheral insensate neuropathy, and patients who are tall have an additional risk regardless of whether or not they have diabetes, according to a study in the November issue of the American Journal of Epidemiology.
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Diabetics Have Significantly More Coronary Restenosis
THURSDAY, Nov. 2 (HealthDay News) -- Diabetics have significantly higher coronary restenosis rates than non-diabetics due to inferior procedural outcomes and increased neointimal cell proliferation, according to a report in the November issue of the American Journal of Cardiology.
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Resveratrol Improves Health, Survival of Obese Mice
WEDNESDAY, Nov. 1 (HealthDay News) -- Resveratrol, a compound found in wine, fruit and nuts, significantly improves the health and survival of obese middle-aged mice fed a high-calorie diet, according to the results of a study published online Nov. 1 in Nature.
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