November 2007 Briefing - Diabetes & Endocrinology
Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for November 2007. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Undocumented Latinos Use Fewer Health Care Services
THURSDAY, Nov. 29 (HealthDay News) -- Citizens of Mexico and other Latin American countries who are not legal U.S. residents are less likely to utilize U.S. medical services than their U.S.-born counterparts and more likely to report negative experiences with the health care system. But they are also less likely to report difficulty obtaining necessary health care, according to a study published in the Nov. 26 issue of the Archives of Internal Medicine.
MR Spectroscopy Distinguishes Between Adrenal Tumor Types
THURSDAY, Nov. 29 (HealthDay News) -- Proton magnetic resonance (MR) spectroscopy using various metabolite ratios is useful in non-invasively distinguishing adrenal carcinomas, pheochromocytomas, adenomas and metastases, according to research published in the December issue of Radiology.
Pattern of Lifetime Drinking May Influence Metabolic Risk
WEDNESDAY, Nov. 28 (HealthDay News) -- People whose alcohol consumption peaks early in life have a modestly increased risk of developing metabolic syndrome compared to people who maintain more moderate intakes throughout a longer period of life, according to research published online Nov. 20 in the Journal of Clinical Endocrinology & Metabolism.
Metabolic Stress May Play Important Role After Stroke
WEDNESDAY, Nov. 28 (HealthDay News) -- Diabetes, lower high-density lipoprotein (HDL) cholesterol and higher homocysteine are all linked with poorer cognitive function in stroke survivors, indicating that metabolic stress may play a role in determining post-stroke recovery, according to research published in the Nov. 27 issue of Neurology.
High-Trauma Fractures Linked to Osteoporosis
TUESDAY, Nov. 27 (HealthDay News) -- New research shows that high-trauma fractures in older individuals are associated with low bone mineral density and increase the risk of subsequent fractures, while a new clinical algorithm can help predict the five-year risk of hip fracture in postmenopausal women. These research findings are published in two studies in the Nov. 28 issue of the Journal of the American Medical Association.
Avandia Affair Holds Important Lessons for Diabetes Care
TUESDAY, Nov. 27 (HealthDay News) -- The Avandia controversy, in which meta-analysis of studies on the drug showed it increased the risk of myocardial infarction and caused the public to question the credibility of the U.S. Food and Drug Administration's drug approval procedures, should result in a new paradigm for development of drugs to treat type 2 diabetes, according to a commentary published in the December issue of Diabetes Care.
Treating Depression Lowers Mortality in Diabetics
TUESDAY, Nov. 27 (HealthDay News) -- Mortality rates are lower among older adults with diabetes and depression if they are treated for their mental illness, according to study findings published in the December issue of Diabetes Care.
Factors in Diabetics' Artery Calcification Examined
TUESDAY, Nov. 27 (HealthDay News) -- Type 2 diabetic patients have a higher risk of coronary artery calcification if they have prior calcification, poor glycemic control or take statins, researchers report in the Dec. 4 issue of the Journal of the American College of Cardiology.
Carb-Rich Diets May Increase Risk of Diabetes in Women
MONDAY, Nov. 26 (HealthDay News) -- Carbohydrate-rich and high glycemic index diets are associated with an increased risk of developing type 2 diabetes in Chinese and black women, whereas adding cereal fiber to the diet may protect against diabetes in black women, according to two studies published Nov. 26 in the Archives of Internal Medicine.
Depression Linked to Low Bone Mass in Younger Women
MONDAY, Nov. 26 (HealthDay News) -- In premenopausal women, the presence of major depressive disorder may be associated with lower bone mineral density, according to a report published in the Nov. 26 issue of the Archives of Internal Medicine.
Early Life Experience Has Little Bearing on Later Activity
MONDAY, Nov. 26 (HealthDay News) -- Few characteristics of early childhood are reliable predictors of physical activity in 11- and 12-year-old children, according to a report published Nov. 23 in BMJ Online First.
New Prediction Tool Targets Osteoporosis in Older Men
FRIDAY, Nov. 23 (HealthDay News) -- A new clinical prediction model for the risk of osteoporosis targets 44 percent of U.S. men aged 50 and older for confirmatory dual-energy x-ray absorptiometry (DXA) scans, researchers report in the November/December issue of the Annals of Family Medicine.
Pedometer Use and Step Goals Linked to Increased Activity
TUESDAY, Nov. 20 (HealthDay News) -- In middle-aged patients, pedometer use is associated with a short-term increase in physical activity, and decreases in body mass index and blood pressure, researchers report in the Nov. 21 issue of the Journal of the American Medical Association.
Albuminuria Risk Factor for Cardiovascular Disease
TUESDAY, Nov. 20 (HealthDay News) -- Patients with stable coronary disease who have albuminuria, even within the normal range, are at increased risk of cardiovascular disease-related and all-cause mortality, according to a study published online Nov. 19 in Circulation: Journal of the American Heart Association.
Women with 'Constitutional Thinness' Have Bone Problems
MONDAY, Nov. 19 (HealthDay News) -- Young adult women who fit the diagnostic criteria for constitutional thinness have a bone mineral density similar to that of young women with anorexia nervosa and significantly lower than that of normal weight women, researchers report in the December issue of the Journal of Clinical Endocrinology & Metabolism.
Pioglitazone Useful Adjunct to Lipid-Lowering Therapy
THURSDAY, Nov. 15 (HealthDay News) -- Non-diabetic patients with familial combined hyperlipidemia have better myocardial glucose utilization and blood flow when they are treated with pioglitazone in combination with conventional lipid-lowering therapy, according to a report published in the Nov. 20 issue of the Journal of the American College of Cardiology.
FDA Adds Avandia Boxed Warning for Heart Attacks
THURSDAY, Nov. 15 (HealthDay News) -- The U.S. Food and Drug Administration announced this week that the manufacturer of Avandia (rosiglitazone) has agreed to add information about a potential increased risk of heart attacks to the drug's existing boxed warning. Avandia is approved for single therapy or in combination with other medications in the treatment of type 2 diabetes.
Protein Tied to High-Fat Diet-Induced Insulin Resistance
TUESDAY, Nov. 13 (HealthDay News) -- Mice lacking JNK1, which is chronically activated in obesity and type 2 diabetes, are protected against high-fat diet-induced insulin resistance by decreased adiposity and obesity-induced inflammation, researchers report in the Nov. 7 issue of Cell Metabolism.
Weight Affects Prostate Cancer Mortality Risk
MONDAY, Nov. 12 (HealthDay News) -- Baseline body mass index affects the odds of dying from prostate cancer, according to the results of a study published online Nov. 12 in the journal Cancer.
Pre-Diabetes Screening of Overweight Adults Supported
THURSDAY, Nov. 8 (HealthDay News) -- In middle-aged and older patients who are overweight or obese, screening for pre-diabetes followed by a Diabetes Prevention Program (DPP) lifestyle intervention has a favorable cost-effectiveness ratio, researchers report in the November issue of Diabetes Care.
Kidney Disease on the Rise in United States
TUESDAY, Nov. 6 (HealthDay News) -- The incidence of chronic kidney disease in the United States is on the rise, especially among those with diabetes and hypertension, researchers report in the Nov. 7 issue of the Journal of the American Medical Association.
Fenofibrate May Lower Retinopathy Risk in Diabetics
TUESDAY, Nov. 6 (HealthDay News) -- Treating individuals with type 2 diabetes with fenofibrate may reduce the progression of diabetic retinopathy, though this effect does not appear to be related to fenofibrate's lipid-lowering effects, according to study findings published online Nov. 6 in the The Lancet.
Sleep Duration Linked to Overweight in Schoolchildren
TUESDAY, Nov. 6 (HealthDay News) -- Short sleep duration independently increases the risk of overweight in children aged 9 and 12, researchers report in the November issue of Pediatrics.
Hyperkalemia Risk Higher in Elderly with Heart Failure
MONDAY, Nov. 5 (HealthDay News) -- Heart failure patients are at higher risk of hyperkalemia if they are older and male, and the risk of hyperkalemia increases in patients treated with candesartan even though the drug also reduces the risk of death and hospitalization, according to a report published in the Nov. 13 issue of the Journal of the American College of Cardiology.
Broad Coalition Needed to Address Obesity Epidemic
FRIDAY, Nov. 2 (HealthDay News) -- A broad approach uniting government, private industry and other societal groups is needed to address the obesity epidemic in the United Kingdom, and enacting the necessary cultural change to combat obesity is indeed feasible, according to an editorial published in the Nov. 3 issue of The Lancet.
CDC: Fewer American Diabetics Developing Heart Disease
FRIDAY, Nov. 2 (HealthDay News) -- There is some good news in Americans' fight against diabetes: affected individuals are doing a better job at self-monitoring their blood glucose, and fewer diabetics report that they have developed heart disease, according to two reports published Nov. 2 in the Morbidity and Mortality Weekly Report.
Races Face Vastly Different Kidney Burden with HIV
THURSDAY, Nov. 1 (HealthDay News) -- Race is a critical factor in determining the risk of end-stage renal disease (ESRD) in people with HIV, with the incidence of ESRD roughly 10 times higher among blacks with HIV than whites with the virus, according to research published in the November issue of the Journal of the American Society of Nephrology.