Strong Association Between Enterovirus and Diabetes Found
Children with type 1 diabetes 10 times more likely to have the viral infection
FRIDAY, Feb. 4 (HealthDay News) -- A review of molecular studies has found a strong association between enterovirus infection and the development of type 1 diabetes; the research has been published online Feb. 3 in BMJ.
Wing-Chi G. Yeung, of the University of New South Wales in Sydney, Australia, and colleagues analyzed 26 case-control studies of 4,448 subjects to review the association between enterovirus infection and type 1 diabetes.
The meta-analysis revealed a significant association between enterovirus infection and the development of type 1 diabetes-related autoimmunity and clinical type 1 diabetes (odds ratios, 3.7 and 9.8, respectively); children diagnosed with type 1 diabetes were nearly 10 times more likely than controls to have enterovirus infection.
"There is a clinically significant association between enterovirus infection, detected with molecular methods, and autoimmunity/type 1 diabetes. Larger prospective studies would be needed to establish a clear temporal relation between enterovirus infection and the development of autoimmunity and type 1 diabetes," the authors write.