Aggressive Approach Identifies Heart Disease in Diabetics

Coronary angiography spots subclinical coronary artery disease in type 2 diabetic patients

FRIDAY, Dec. 30 (HealthDay News) -- An aggressive diagnostic approach including angiography can identify subclinical coronary artery disease (CAD) in patients with type 2 diabetes, according to a study in the January issue of the Journal of the American College of Cardiology.

Roldano Scognamiglio, M.D., of the University of Padua Medical School in Padua, Italy, and colleagues studied 1,899 asymptomatic patients with type 2 diabetes. These included 1,121 (group A) with two or more CAD risk factors, and 778 (group B) with one or fewer CAD risk factors.

The researchers found that about 60% of both groups had abnormal myocardial contrast echocardiography (MCE) and about 65% of both groups had significant CAD. However, group B patients were less likely to have three-vessel disease, diffuse disease and vessel occlusion than group A. About 45% of group A patients could not have revascularization due to coronary anatomy.

"An 'aggressive' diagnostic approach, requiring coronary angiography in asymptomatic type 2 diabetes mellitus patients with [one or fewer] associated risk factors for CAD and abnormal MCE, identified patients with a subclinical CAD characterized by a more favorable angiographic anatomy," the authors write.

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