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Metabolic Syndrome Increases Death After Bypass Surgery

Risk also higher in those with metabolic syndrome plus diabetes

FRIDAY, Aug. 24 (HealthDay News) -- Patients with metabolic syndrome alone or with diabetes have a higher risk of death after coronary artery bypass grafting surgery than those who do not, according to the results of a study published in the Aug. 28 issue of the Journal of the American College of Cardiology.

Patrick Mathieu, M.D., from the Hopital Laval in Quebec, Canada, and colleagues retrospectively examined mortality in 5,304 patients who had undergone coronary artery bypass grafting surgery, of which 46 percent had metabolic syndrome.

The researchers found that after adjusting for other risk factors, the risk of operative mortality was significantly higher in those with metabolic syndrome (relative risk, 2.36) and metabolic syndrome plus diabetes (relative risk, 2.69). The risk was not significantly higher in patients with diabetes alone. About 2.4 percent of patients with metabolic syndrome died after surgery, compared with 0.9 percent of those without metabolic syndrome.

"This is the first study to report that metabolic syndrome is a highly prevalent and powerful risk factor for operative mortality in patients undergoing a coronary artery bypass grafting surgery," Mathieu and colleagues conclude.

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