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Cutting Out Soda Helps Weight Loss Efforts

Fructose-sweetened drinks can be worse for obese people than glucose-based drinks

MONDAY, April 6 (HealthDay News) -- Limiting consumption of sugar-sweetened drinks helps with weight loss, according to a study published online April 1 in the American Journal of Clinical Nutrition, while another study published in the Journal of Clinical Endocrinology & Metabolism found that obese people are at higher risk of diabetes and cardiovascular disease if they consume drinks sweetened with fructose rather than glucose.

Liwei Chen, M.D., Ph.D., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, and colleagues conducted a study of 810 adults by controlling their intake of liquid calories, and found that a 100 kcal/day reduction in intake from the baseline intake of 19 percent of their daily calories, or 356 kcal/day, was associated with 0.25 kg of weight loss at six months, and that subjects lost more weight when they reduced liquid calorie intake versus solid calorie intake. Of the various beverages studied, only sugar-sweetened beverages were significantly associated with weight.

Karen L. Teff, Ph.D., of the University of Pennsylvania in Philadelphia, and colleagues conducted a study of nine obese men and eight obese women with a body mass index of over 30 kg/m2, who were given meals served with either glucose-sweetened or fructose-sweetened beverages accounting for 30 percent of calorie intake. The researchers found that after fructose consumption, the subjects had blunted diurnal leptin profiles and increased post-prandial triglyceride concentrations, and also secreted less insulin than after glucose consumption.

"Over-consumption of dietary fructose may exacerbate the adverse metabolic profiles in obese individuals, particularly those with existing insulin resistance, and may therefore increase the risks for developing diabetes and cardiovascular disease," Teff and colleagues write.

Abstract -- Chen
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Abstract -- Teff
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