Obesity Alone Not Significant Predictor of Mortality

Diabetes mellitus better predictor of the risk of organ failure and mortality

MONDAY, Sept. 25 (HealthDay News) -- Obesity alone is not strongly predictive of acute organ failure or death, but diabetes mellitus is significantly associated with both, according to a paper in the September issue of Critical Care.

Katarina Slynkova, M.D., of the University of Kentucky Medical Center in Lexington, Ky., and colleagues analyzed data from 15,408 participants in the Atherosclerosis Risk in Communities study. The researchers evaluated the development of acute organ failure within three years of the baseline examination; in-hospital death concomitant with acute organ failure; and death at three years for all subjects and for those with acute organ failure.

The investigators found that patients with a body mass index (BMI) of 30 or more were more likely to be diabetic. Diabetics had three times more incident organ failure than non-diabetics. Diabetics who experienced organ failure were twice as likely to die in-hospital as non-diabetics. Body mass index alone was not predictive of organ failure.

"Results of this study indicate that the presence of diabetes mellitus, rather than an increased BMI, accounts for a higher risk of acute organ failure and associated mortality," they conclude.

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