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Type 2 Diabetes Associated with Parkinson Disease Risk

More study needed to clarify link between two conditions

WEDNESDAY, March 28 (HealthDay News) -- Type 2 diabetes is associated with an increased risk for Parkinson disease in old age, according to a report in the April issue of Diabetes Care.

Gang Hu, M.D., Ph.D., of the National Public Health Institute in Helsinki, Finland, prospectively followed 51,522 Finnish men and women aged 25 to 74 years without a history of Parkinson disease.

Over 600 men and women developed Parkinson disease during a mean follow-up of 18 years. After adjustments, type 2 diabetes at baseline was associated with a 1.8-fold increase in the risk of Parkinson disease in men and a 1.93-fold increase in risk for women. The association was confirmed in a stratified subgroup analysis.

"The biological mechanisms behind the association of type 2 diabetes with the risk of Parkinson disease are, however, not understood at present," the authors write. "Further studies to replicate our findings in other populations should be acknowledged."

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