New Diabetes Guideline Released

It addresses newer therapeutic agents in type 2 diabetes

WEDNESDAY, Oct. 29 (HealthDay News) -- An updated guideline provides recommendations for the use of newer classes of medications that treat hyperglycemia in type 2 diabetes, according to an online report in the December issue of Diabetes Care.

David M. Nathan, M.D., of Massachusetts General Hospital in Boston and colleagues provide an update to the consensus algorithm for the medical management of type 2 diabetes published in 2006. The update focuses on new classes of medications. While the authors continue to support the major features of the original algorithm, the writing group for the American Diabetes Association and the European Association for the Study of Diabetes felt a revision addressing new agents was warranted.

While lifestyle modification and intensive metformin therapy remain the initial treatment of choice at diagnosis, the consensus statement offers other possible therapies if this does not lead to optimal control. The guideline also provides guidance for combining therapies. The main goals of the guideline remain: 1) maintenance of normoglycemia, 2) aggressive initial therapy with lifestyle modification and metformin, 3) prompt addition of new medications when target glycemic goals are not met, and 4) early addition of insulin.

"Although new classes of medications and numerous combinations have been demonstrated to lower glycemia, current-day management has failed to achieve and maintain the glycemic levels most likely to provide optimal healthcare status for people with diabetes," the authors conclude.

Several of the authors have received honoraria from or serve on advisory boards for companies developing diabetes treatments.

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